Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4346472 | 0.82 | LMNA (0.44) | LMNAHSD17B10CTSKTSHRCYP3A4 | |
| SCHEMBL28890479 | 0.78 | LMNA (0.40) | LMNAHSD17B10CTSKTSHRCYP3A4 | |
| SCHEMBL28513794 | 0.78 | LMNA (0.40) | LMNAHSD17B10CTSKTSHRCYP3A4 | |
| SCHEMBL29063527 | 0.78 | LMNA (0.40) | LMNAHSD17B10CTSKTSHRCYP3A4 | |
| SCHEMBL1811804 | 0.78 | LMNA (0.40) | LMNAHSD17B10CTSKTSHRCYP3A4 | |
| SCHEMBL29063462 | 0.75 | LMNA (0.42) | LMNAHSD17B10TSHRCYP3A4NFKB1 | |
| SCHEMBL29063461 | 0.75 | LMNA (0.42) | LMNAHSD17B10TSHRCYP3A4NFKB1 | |
| SCHEMBL29958378 | 0.74 | FDPS (0.38) | MEN1MAPTKMT2AATML3MBTL1 | |
| SCHEMBL18109402 | 0.74 | FDPS (0.38) | MEN1MAPTKMT2AATML3MBTL1 | |
| SCHEMBL18109397 | 0.74 | FDPS (0.38) | MEN1MAPTKMT2AATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115362155-B | Arylamine derivative, preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-115362155-A | Arylamine derivatives, and preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2022-11-18 | — | — | CN | disclosed |