SCHEMBL28890673

SCHEMBL28890673

CCCCCCCCCCCSCc1ccc(I)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.38
ESR1 P03372 3/20 0.36
ESR2 Q92731 1/20 0.36
TP53 P04637 3/20 0.36
LMNA P02545 3/20 0.36
ADRA2A P08913 2/20 0.36
ADORA3 P0DMS8 2/20 0.36
TACR2 P21452 2/20 0.36
SLC6A2 P23975 2/20 0.36
SLC6A4 P31645 2/20 0.36
SLC6A3 Q01959 2/20 0.36
HSD17B10 Q99714 2/20 0.36
MAPT P10636 2/20 0.36
CES2 O00748 1/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
SHBG P04278 1/20 0.36
CYP3A4 P08684 1/20 0.36
HSPD1 P10809 1/20 0.36
ADRB3 P13945 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29388293 0.90 ESR1 (0.42) ESR1ESR2TP53LMNAADRA2A
SCHEMBL6075249 0.90 ESR1 (0.42) ESR1ESR2TP53LMNAADRA2A
SCHEMBL8999593 0.88 TYR (0.41) ESR1ESR2TP53LMNAADRA2A
SCHEMBL8019398 0.82 LMNA (0.42) TP53LMNAMAPTKDM4EALDH1A1
SCHEMBL27839570 0.81 ESR1 (0.58) ESR1ESR2TP53LMNAADRA2A
SCHEMBL27820086 0.81 ESR1 (0.58) ESR1ESR2TP53LMNAADRA2A
SCHEMBL20239385 0.81 ESR1 (0.58) ESR1ESR2TP53LMNAADRA2A
SCHEMBL27820038 0.81 ESR1 (0.58) ESR1ESR2TP53LMNAADRA2A
SCHEMBL7164995 0.81 MAPT (0.44) ESR1ESR2TP53LMNAADRA2A
SCHEMBL1312718 0.81 MAPT (0.44) ESR1ESR2TP53LMNAADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115354350-A Method for electrocatalytic in-situ nitration of halogenated aromatic hydrocarbon 平顶山学院 2022-11-18 CN disclosed