Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8999593 | 0.93 | TYR (0.41) | LMNAMAPTALDH1A1KDM4ETP53 | |
| SCHEMBL29281816 | 0.91 | RECQL (0.50) | LMNAMAPTALDH1A1KDM4ERECQL | |
| SCHEMBL28263074 | 0.91 | LPL (0.41) | LMNAMAPTALDH1A1KDM4ECYP2C19 | |
| SCHEMBL29388293 | 0.91 | ESR1 (0.42) | LMNAMAPTALDH1A1KDM4ETP53 | |
| SCHEMBL6075249 | 0.91 | ESR1 (0.42) | LMNAMAPTALDH1A1KDM4ETP53 | |
| SCHEMBL10745266 | 0.89 | ESR1 (0.52) | LMNAMAPTALDH1A1KDM4ETP53 | |
| SCHEMBL14443894 | 0.89 | CYP1A2 (0.49) | LMNAALDH1A1KDM4ETDP1CYP2C19 | |
| SCHEMBL425182 | 0.89 | SMN1; SMN2 (0.50) | LMNAALDH1A1CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL14443962 | 0.89 | PSMD14 (0.42) | LMNAMAPTALDH1A1TP53HTT | |
| SCHEMBL2561339 | 0.89 | CYP2C19 (0.52) | LMNAMAPTALDH1A1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705857-B1 | A process for producing polymers of alpha,omega-unsaturated conjugated compounds | AVENTIS RES & TECH GMBH & CO (DE) | 2000-01-19 | — | — | EP | disclosed |
| US-5763539-A | Process for producing polymers of α,ω-unsaturated conjugated compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-06-09 | — | — | US | disclosed |
| EP-0705857-A2 | A process for producing polymers of alpha,omega-unsaturated conjugated compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-04-10 | — | — | EP | disclosed |