Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.55 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | DRD4 | P21917 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | ESRRA | P11474 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CD74 | P04233 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13255921 | 0.83 | CA1 (0.45) | P2RX7NOTUML3MBTL1MAOANPC1 | |
| SCHEMBL16651937 | 0.79 | CYP2A6 (0.47) | P2RX7L3MBTL1NPC1RAB9AMIF | |
| SCHEMBL12352631 | 0.77 | NOTUM (0.60) | NOTUMCA12CA9KEAP1NFE2L2 | |
| SCHEMBL2629357 | 0.74 | P2RX7 (0.55) | P2RX7NOTUML3MBTL1MAOADRD2 | |
| SCHEMBL12959177 | 0.74 | P2RX7 (0.55) | P2RX7NOTUML3MBTL1MAOADRD2 | |
| SCHEMBL23028378 | 0.74 | NOTUM (0.58) | P2RX7NOTUML3MBTL1MAOADRD2 | |
| SCHEMBL16090354 | 0.74 | P2RX7 (0.55) | P2RX7NOTUML3MBTL1MAOADRD2 | |
| SCHEMBL6030190 | 0.74 | NOTUM (0.58) | P2RX7NOTUML3MBTL1MAOADRD2 | |
| SCHEMBL17039112 | 0.74 | P2RX7 (0.55) | P2RX7NOTUML3MBTL1MAOADRD2 | |
| SCHEMBL12443625 | 0.74 | P2RX7 (0.55) | P2RX7NOTUML3MBTL1MAOADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11826435-B2 | Conduritol aziridine derivatives and uses thereof | UNIVERSITY OF SASKATCHEWAN (CA) | 2023-11-28 | — | — | US | disclosed |
| US-20210052752-A1 | CONDURITOL AZIRIDINE DERIVATIVES AND USES THEREOF | UNIVERSITY OF SASKATCHEWAN (CA) | 2021-02-25 | — | — | US | disclosed |
| EP-2643023-B1 | RADIOIODINATION METHOD | GE HEALTHCARE LTD (GB) | 2018-07-18 | — | — | EP | disclosed |
| US-7858800-B2 | Biaryl derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-12-28 | — | — | US | disclosed |
| US-20070191389-A1 | Biaryl derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-08-16 | — | — | US | disclosed |
| EP-1764362-A1 | BIARYL DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-03-21 | — | — | EP | disclosed |
| WO-2007015812-A2 | HIV REVERSE TRANSCRIPTASE INHIBITORS | MERCK & CO., INC. (US) | 2007-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11826435-B2 | Conduritol aziridine derivatives and uses thereof | GAA, MAN2B1, GBA3 | P2RX7 893/4885NOTUM 1059/4885L3MBTL1 4857/4885 |
| US-20070191389-A1 | Biaryl derivatives | GRM1, GRIN1, GRIN2B | P2RX7 1337/4885NOTUM 3935/4885L3MBTL1 286/4885 |
| US-20210052752-A1 | CONDURITOL AZIRIDINE DERIVATIVES AND USES THEREOF | GAA, MAN2B1, GBA3 | P2RX7 893/4885NOTUM 1059/4885L3MBTL1 4857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.