SCHEMBL541468

SCHEMBL541468

Sc1cn(-c2ccccc2)nn1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ P2RX7 Q99572 1/20 0.55
▸ NOTUM Q6P988 3/20 0.53
▸ MAOA P21397 1/20 0.53
▸ L3MBTL1 Q9Y468 1/20 0.53
▸ DRD2 P14416 2/20 0.45
▸ DRD4 P21917 2/20 0.45
▸ DRD3 P35462 2/20 0.45
▸ ESRRA P11474 1/20 0.42
▸ CD74 P04233 1/20 0.41
▸ MIF P14174 1/20 0.41
▸ CA12 O43570 2/20 0.41
▸ CA1 P00915 2/20 0.41
▸ CA2 P00918 2/20 0.41
▸ CA9 Q16790 2/20 0.41
▸ HDAC8 Q9BY41 1/20 0.40
▸ KEAP1 Q14145 1/20 0.40
▸ NFE2L2 Q16236 1/20 0.40
▸ KDM1A O60341 1/20 0.40
▸ NPC1 O15118 1/20 0.40
▸ GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5675088 0.98 P2RX7 (0.53) P2RX7NOTUMMAOAL3MBTL1DRD2
SCHEMBL2889068 0.74 P2RX7 (0.55) P2RX7NOTUMMAOAL3MBTL1DRD2
SCHEMBL12959177 0.74 P2RX7 (0.55) P2RX7NOTUMMAOAL3MBTL1DRD2
SCHEMBL17039112 0.74 P2RX7 (0.55) P2RX7NOTUMMAOAL3MBTL1DRD2
SCHEMBL12443625 0.74 P2RX7 (0.55) P2RX7NOTUMMAOAL3MBTL1DRD2
SCHEMBL23028378 0.74 NOTUM (0.58) P2RX7NOTUMMAOAL3MBTL1DRD2
SCHEMBL16090354 0.74 P2RX7 (0.55) P2RX7NOTUMMAOAL3MBTL1DRD2
SCHEMBL6030190 0.74 NOTUM (0.58) P2RX7NOTUMMAOAL3MBTL1DRD2
SCHEMBL2629357 0.74 P2RX7 (0.55) P2RX7NOTUMMAOAL3MBTL1DRD2
SCHEMBL2358990 0.74 P2RX7 (0.55) P2RX7NOTUMMAOAL3MBTL1DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8518478-B2 Conductive fibers and a method of manufacturing the same INKTEC CO., LTD. (KR) 2013-08-27 — — US claimed
US-20110003153-A1 CONDUCTIVE FIBERS AND A METHOD OF MANUFACTURING THE SAME INKTEC CO., LTD. (KP) 2011-01-06 — — US claimed
WO-2008103013-A1 CONDUCTIVE FIBERS AND A METHOD OF MANUFACTURING THE SAME INKTEC CO., LTD. (KR) 2008-08-28 — — WO claimed
US-11389456-B2 Compounds and methods for treating oxalate-related diseases OXALURX, INC. (US) 2022-07-19 — — US disclosed
US-20200390778-A1 COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES OXALURX, INC. 2020-12-17 — — US disclosed
WO-2019165159-A1 COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES OXALURX, INC. (US) 2019-08-29 — — WO disclosed
US-8518478-B2 Conductive fibers and a method of manufacturing the same INKTEC CO., LTD. (KR) 2013-08-27 — — US disclosed
EP-2413696-A1 COMPOSITIONS FOR TREATMENT OF ALZHEIMER'S DISEASE Mount Sinai School Of Medicine Of New York University (US) 2012-02-08 — — EP disclosed
US-20110003153-A1 CONDUCTIVE FIBERS AND A METHOD OF MANUFACTURING THE SAME INKTEC CO., LTD. (KP) 2011-01-06 — — US disclosed
WO-2010114636-A1 COMPOSITIONS FOR TREATMENT OF ALZHEIMER'S DISEASE MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY (US) 2010-10-07 — — WO disclosed
WO-2008103013-A1 CONDUCTIVE FIBERS AND A METHOD OF MANUFACTURING THE SAME INKTEC CO., LTD. (KR) 2008-08-28 — — WO disclosed
US-6756191-B2 LIGHT-SENSITIVITY AND EXCELLENT STORAGE STABILITY KONICA CORPORATION (JP) 2004-06-29 — — US disclosed
US-20030157447-A1 Silver halide photographic light-sensitive emulsion and silver halide photographic light-sensitive material using thereof KONICA CORPORATION (JP) 2003-08-21 — — US disclosed
EP-1283439-A1 Silver halide photographic light-sensitive emulsion and silver halide photographic light-sensitive material Konica Corporation (JP) 2003-02-12 — — EP disclosed
EP-0712036-B1 Silver halide light-sensitive photographic screen-film system with enhanced image quality for rapid processing applications in mammography AGFA GEVAERT NV (BE) 1999-07-28 — — EP disclosed
EP-0712036-A1 Silver halide light-sensitive photographic screen-film system with enhanced image quality for rapid processing applications in mammography AGFA-GEVAERT N.V. (BE) 1996-05-15 — — EP disclosed
EP-0610609-A1 Silver halide light-sensitive photographic material with enhanced image quality for rapid processing applications in mammography AGFA-GEVAERT N.V. (BE) 1994-08-17 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200390778-A1 COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES XDH, PNPO, LOX P2RX7 2313/4885NOTUM 1065/4885MAOA 110/4885
US-11389456-B2 Compounds and methods for treating oxalate-related diseases XDH, PNPO, LOX P2RX7 2313/4885NOTUM 1065/4885MAOA 110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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