Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12138257 | 0.79 | AR (0.46) | ALDH1A1HSD17B10ALOX15TSHRPOLB | |
| SCHEMBL22372423 | 0.73 | AR (0.49) | ALDH1A1HSD17B10HPGDALOX15TSHR | |
| SCHEMBL3277444 | 0.71 | ALDH1A1 (0.58) | ALDH1A1HSD17B10HPGDPSMB8ALOX15 | |
| SCHEMBL17951532 | 0.71 | AR (0.54) | ALDH1A1HSD17B10HPGDALOX15TSHR | |
| SCHEMBL38658790 | 0.67 | KDM4E (0.61) | ALDH1A1HSD17B10HPGDPSMB8ALOX15 | |
| SCHEMBL16208357 | 0.67 | ALDH1A1 (0.56) | ALDH1A1HSD17B10HPGDPSMB8ALOX15 | |
| SCHEMBL29874884 | 0.67 | ALDH1A1 (0.56) | ALDH1A1HSD17B10HPGDPSMB8ALOX15 | |
| SCHEMBL16274672 | 0.67 | ALDH1A1 (0.56) | ALDH1A1HSD17B10HPGDPSMB8ALOX15 | |
| SCHEMBL4030881 | 0.67 | KDM4E (0.61) | ALDH1A1HSD17B10HPGDPSMB8ALOX15 | |
| SCHEMBL8991542 | 0.67 | TERT (0.42) | ALDH1A1HSD17B10ALOX15TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108689946-B | 2-substituted sulfenyl acetamide compound and preparation method and application thereof | 中国科学院上海药物研究所 | 2022-10-18 | — | — | CN | disclosed |