Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 19/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.58 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.56 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28411972 | 0.87 | HDAC6 (0.78) | HDAC6HDAC3HDAC1HDAC7HDAC2 | |
| SCHEMBL28411809 | 0.80 | HDAC6 (0.56) | HDAC6HDAC3HDAC1HDAC7HDAC2 | |
| SCHEMBL16646754 | 0.79 | HDAC6 (0.76) | HDAC6HDAC3HDAC1HDAC7HDAC2 | |
| SCHEMBL28408662 | 0.78 | HDAC6 (0.74) | HDAC6HDAC3HDAC1HDAC7HDAC2 | |
| SCHEMBL10050234 | 0.78 | HDAC6 (0.82) | HDAC6HDAC3HDAC1HDAC7HDAC2 | |
| SCHEMBL16644092 | 0.78 | HDAC6 (0.73) | HDAC6HDAC3HDAC1HDAC7HDAC2 | |
| SCHEMBL2223535 | 0.76 | HDAC6 (0.84) | HDAC6HDAC3HDAC1HDAC7HDAC2 | |
| SCHEMBL28975352 | 0.75 | HDAC6 (0.53) | HDAC6HDAC3HDAC1HDAC7HDAC2 | |
| SCHEMBL28975349 | 0.75 | HDAC6 (0.75) | HDAC6HDAC3HDAC1HDAC7HDAC2 | |
| SCHEMBL2224178 | 0.75 | HDAC6 (1.00) | HDAC6HDAC3HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110885316-A | Sulfhydryl compound as histone deacetylase inhibitor and application thereof | 上海中泽医药科技有限公司 | 2020-03-17 | — | — | CN | disclosed |