Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 6/20 | 0.40 |
| ▸ | ERN1 | O75460 | 4/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 5/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 5/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 5/20 | 0.34 |
| ▸ | STK17B | O94768 | 2/20 | 0.34 |
| ▸ | BCL2 | P10415 | 2/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.34 |
| ▸ | CDK7 | P50613 | 2/20 | 0.34 |
| ▸ | DAPK1 | P53355 | 2/20 | 0.34 |
| ▸ | CAMK4 | Q16566 | 2/20 | 0.34 |
| ▸ | MAPK15 | Q8TD08 | 2/20 | 0.34 |
| ▸ | PNPLA2 | Q96AD5 | 2/20 | 0.34 |
| ▸ | HIPK3 | Q9H422 | 2/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL609426 | 0.82 | ERN1 (0.49) | ERN1PTPRC | |
| SCHEMBL7525014 | 0.73 | ERN1 (0.48) | ERN1PTPRC | |
| SCHEMBL7533951 | 0.73 | ERN1 (0.51) | ERN1PTPRC | |
| SCHEMBL97412 | 0.71 | ERN1 (0.51) | ERN1PTPRC | |
| SCHEMBL7528504 | 0.70 | CA1 (0.49) | ERN1 | |
| SCHEMBL28232720 | 0.69 | PIM1 (0.41) | ERN1PIM1PIM3PIM2 | |
| SCHEMBL28231810 | 0.69 | ERN1 (0.47) | ERN1 | |
| SCHEMBL15093973 | 0.69 | ALDH1A3 (0.45) | PIM1PIM3PIM2 | |
| SCHEMBL28918738 | 0.69 | ERN1 (0.49) | ERN1PTPRC | |
| SCHEMBL7453513 | 0.68 | TRIM24 (0.55) | PRKDCPIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108586457-B | indole carbocycle dearomatization synthesis method based on nitrogen atom α hydrogen migration strategy | 青岛农业大学 | 2020-05-19 | — | — | CN | disclosed |