SCHEMBL28891706

SCHEMBL28891706

CCCCCCC(S)C[SiH](OCC)OCC

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.35
LMNA P02545 1/20 0.33
DNM1 Q05193 2/20 0.32
SMPD1 P17405 3/20 0.32
TSHR P16473 1/20 0.31
THRB P10828 1/20 0.31
ZDHHC7 Q9NXF8 1/20 0.31
GPR84 Q9NQS5 3/20 0.31
FDPS P14324 3/20 0.31
SPHK1 Q9NYA1 1/20 0.31
FFAR1 O14842 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19511682 1.00 OPRM1 (0.35) OPRM1LMNADNM1SMPD1TSHR
SCHEMBL28423755 0.92 MMP13 (0.31) DNM1
SCHEMBL28419606 0.84
SCHEMBL28425727 0.82 ZDHHC7 (0.35) OPRM1LMNADNM1SMPD1TSHR
SCHEMBL28418343 0.82 ZDHHC7 (0.35) OPRM1LMNADNM1SMPD1TSHR
SCHEMBL28428331 0.82 ZDHHC7 (0.35) OPRM1LMNADNM1SMPD1TSHR
SCHEMBL19512099 0.82 ZDHHC7 (0.35) OPRM1LMNADNM1SMPD1TSHR
SCHEMBL22551439 0.80 OPRM1 (0.33) OPRM1LMNADNM1ZDHHC7
SCHEMBL28418740 0.79 OPRM1 (0.34) OPRM1LMNADNM1SMPD1ZDHHC7
SCHEMBL28421148 0.79 OPRM1 (0.34) OPRM1LMNADNM1SMPD1ZDHHC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111233916-A Long carbon chain sulfur-containing silane coupling agent, and preparation method and application thereof 南京曙光精细化工有限公司 2020-06-05 CN disclosed