SCHEMBL28891724

SCHEMBL28891724

CCCCC[SiH2]OC(=O)CCCCCCCCCCCCCCCCC(C)C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.49
MAPT P10636 2/20 0.45
DGKA P23743 1/20 0.43
MAPK1 P28482 1/20 0.42
CETP P11597 1/20 0.41
ALDH1A1 P00352 1/20 0.41
PAM P19021 2/20 0.40
FFAR4 Q5NUL3 1/20 0.40
FFAR1 O14842 1/20 0.40
TLR2 O60603 1/20 0.40
KDM4E B2RXH2 1/20 0.40
DUSP3 P51452 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
LPAR6 P43657 1/20 0.38
LPAR1 Q92633 1/20 0.38
LPAR4 Q99677 1/20 0.38
LPAR5 Q9H1C0 1/20 0.38
LPAR2 Q9HBW0 1/20 0.38
LPAR3 Q9UBY5 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28416480 1.00 LMNA (0.49) LMNAMAPTDGKAMAPK1CETP
SCHEMBL28419000 1.00 LMNA (0.49) LMNAMAPTDGKAMAPK1CETP
SCHEMBL28423840 0.95 LMNA (0.46) LMNAMAPTDGKAMAPK1ALDH1A1
SCHEMBL28423751 0.93 LMNA (0.43) LMNAMAPTDGKAMAPK1CETP
SCHEMBL28419924 0.93 LMNA (0.43) LMNAMAPTDGKAMAPK1CETP
SCHEMBL28428186 0.86 FOLH1 (0.35) LMNAMAPTCETPTLR2MEN1
SCHEMBL6663763 0.85 DGKA (0.48) LMNAMAPTDGKAMAPK1ALDH1A1
SCHEMBL6662620 0.85 DGKA (0.48) LMNAMAPTDGKAMAPK1ALDH1A1
SCHEMBL28424726 0.84 LMNA (0.41) LMNAMAPTDGKAMAPK1ALDH1A1
SCHEMBL6659112 0.83 DGKA (0.45) LMNADGKAALDH1A1FFAR4FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111233916-A Long carbon chain sulfur-containing silane coupling agent, and preparation method and application thereof 南京曙光精细化工有限公司 2020-06-05 CN disclosed