SCHEMBL28891979

SCHEMBL28891979

COc1ccc2ccc3c(O)ccc4ccc1c2c43

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 2/20 0.48
EPAS1 Q99814 1/20 0.48
PPARG P37231 1/20 0.44
MAPT P10636 5/20 0.44
GAA P10253 4/20 0.44
NQO1 P15559 1/20 0.41
MAOB P27338 1/20 0.41
MEN1 O00255 1/20 0.40
NPC1 O15118 1/20 0.40
HSP90AA1 P07900 1/20 0.40
RAB9A P51151 1/20 0.40
KMT2A Q03164 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
ALDH1A1 P00352 2/20 0.39
CYP1A2 P05177 2/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C19 P33261 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28892026 1.00 HIF1A (0.48) HIF1AEPAS1PPARGMAPTGAA
SCHEMBL19999172 0.87 NQO1 (0.50) HIF1AEPAS1MAPTGAANQO1
SCHEMBL29876078 0.87 NQO1 (0.50) HIF1AEPAS1MAPTGAANQO1
SCHEMBL10392528 0.87 NQO1 (0.50) HIF1AEPAS1MAPTGAANQO1
SCHEMBL5533274 0.85 PPARG (0.50) HIF1APPARGMAPTGAANQO1
SCHEMBL22170120 0.83 HPGD (0.38) HIF1AEPAS1PPARGMAPTGAA
SCHEMBL22170101 0.80 HSD17B10 (0.50) MAPTL3MBTL1ALDH1A1CYP1A2CYP3A4
SCHEMBL30849786 0.80 HSD17B10 (0.50) MAPTL3MBTL1ALDH1A1CYP1A2CYP3A4
SCHEMBL16144679 0.80 HSD17B10 (0.50) MAPTL3MBTL1ALDH1A1CYP1A2CYP3A4
SCHEMBL14444293 0.79 PPARG (0.46) PPARGMAPTGAANQO1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119296764-A Marker for detecting sensitivity of tumor radiotherapy and screening method and application thereof 福建医科大学附属协和医院 2025-01-10 CN disclosed
CN-119165078-A Combined marker for detecting tumor radiotherapy sensitivity and application thereof 福建医科大学附属协和医院 2024-12-20 CN disclosed
CN-115202153-A Hard mask composition, hard mask layer and method for forming pattern 三星SDI株式会社 2022-10-18 CN disclosed
US-20220315790-A1 HARDMASK COMPOSITION, HARDMASK LAYER AND METHOD OF FORMING PATTERNS SAMSUNG SDI CO., LTD. (KR) 2022-10-06 US disclosed