SCHEMBL5533274

SCHEMBL5533274

COc1ccc(O)c2ccccc12.Oc1ccc2ccc3cccc4ccc1c2c34

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 2/20 0.50
GAA P10253 2/20 0.47
MEN1 O00255 1/20 0.47
NPC1 O15118 1/20 0.47
HSP90AA1 P07900 1/20 0.47
RAB9A P51151 1/20 0.47
KMT2A Q03164 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
MAPT P10636 2/20 0.46
CETP P11597 2/20 0.46
CYP1A2 P05177 2/20 0.45
ALDH1A1 P00352 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2C19 P33261 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
HIF1A Q16665 1/20 0.45
HSD17B10 Q99714 1/20 0.45
NQO1 P15559 1/20 0.44
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28892026 0.85 HIF1A (0.48) PPARGGAAMEN1NPC1HSP90AA1
SCHEMBL28891979 0.85 HIF1A (0.48) PPARGGAAMEN1NPC1HSP90AA1
1-Naphthol SCHEMBL8587451 0.83 CYP1A2 (0.61) PPARGGAAMEN1NPC1HSP90AA1
SCHEMBL217255 0.83 IDO1 (0.59) GAAMEN1HSP90AA1KMT2AMAPT
SCHEMBL2351815 0.81 HPGD (0.54) PPARGGAAMEN1HSP90AA1KMT2A
Methyl Alcohol SCHEMBL27974596 0.81 IDO1 (0.56) GAAMEN1HSP90AA1KMT2AMAPT
SCHEMBL11075614 0.79 MAPT (0.51) PPARGKMT2AMAPTCETPCYP1A2
Methyl Alcohol SCHEMBL28626522 0.79 HPGD (0.56) MEN1KMT2AL3MBTL1MAPTCYP1A2
SCHEMBL29571791 0.79 HPGD (0.55) MEN1KMT2AL3MBTL1MAPTCYP1A2
SCHEMBL218996 0.79 HPGD (0.55) MEN1KMT2AL3MBTL1MAPTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101914620-B Method for analysis of molecules PACIFIC BIOSCIENCES CALIFORNIA 2014-02-12 CN disclosed
CN-101199241-B Apparatus and method for molecular analysis PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2012-02-22 CN disclosed
CN-101914620-A The apparatus and method of analysis of molecules PACIFIC BIOSCIENCES CALIFORNIA 2010-12-15 CN disclosed
CN-101199241-A Apparatus and method for molecular analysis PACIFIC BIOSCIENCES CALIFORNIA (US) 2008-06-11 CN disclosed
EP-1844328-A2 USE OF REVERSIBLE EXTENSION TERMINATOR IN NUCLEIC ACID SEQUENCING Pacific Biosciences of California, Inc. (US) 2007-10-17 EP disclosed
EP-1790202-A2 APPARATUS AND METHOD FOR ANALYSIS OF MOLECULES Pacific Biosciences of California, Inc. (US) 2007-05-30 EP disclosed
WO-2006083751-A2 USE OF REVERSIBLE EXTENSION TERMINATOR IN NUCLEIC ACID SEQUENCING PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2006-08-10 WO disclosed
WO-2006044078-A2 APPARATUS AND METHOD FOR ANALYSIS OF MOLECULES PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2006-04-27 WO disclosed