Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1LG2 | Q9BQ51 | 3/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1557903 | 0.84 | KMT2A (0.32) | PDCD1LG2CD274MEN1KMT2AP2RX7 | |
| SCHEMBL15779164 | 0.80 | KDM1A (0.40) | MEN1KMT2AP2RX7 | |
| SCHEMBL31308967 | 0.79 | KMT2A (0.40) | MEN1KMT2AHTR2AHTR2CP2RX7 | |
| SCHEMBL22093865 | 0.79 | KMT2A (0.40) | MEN1KMT2AHTR2AHTR2CP2RX7 | |
| SCHEMBL31551835 | 0.78 | HTR2A (0.39) | PDCD1LG2CD274MEN1KMT2AHTR2A | |
| SCHEMBL24607728 | 0.77 | P2RX7 (0.38) | MEN1KMT2AHTR2AHTR2CP2RX7 | |
| SCHEMBL29988047 | 0.77 | HTR2A (0.43) | PDCD1LG2CD274MEN1KMT2AHTR2A | |
| SCHEMBL29751546 | 0.77 | P2RX7 (0.38) | MEN1KMT2AHTR2AHTR2CP2RX7 | |
| SCHEMBL29129295 | 0.77 | HTR2A (0.43) | PDCD1LG2CD274MEN1KMT2AHTR2A | |
| SCHEMBL30002930 | 0.77 | HTR2A (0.34) | MEN1KMT2AHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232144-B | Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |