Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.43 |
| ▸ | HTR2C | P28335 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29988047 | 1.00 | HTR2A (0.43) | HTR2AHTR2CMEN1KMT2APDCD1LG2 | |
| SCHEMBL22093865 | 0.84 | KMT2A (0.40) | HTR2AHTR2CMEN1KMT2AMAPK1 | |
| SCHEMBL31308967 | 0.84 | KMT2A (0.40) | HTR2AHTR2CMEN1KMT2AMAPK1 | |
| SCHEMBL31048634 | 0.84 | MEN1 (0.46) | HTR2AHTR2CMEN1KMT2A | |
| SCHEMBL29129294 | 0.83 | MEN1 (0.38) | HTR2AHTR2CMEN1KMT2APDCD1LG2 | |
| SCHEMBL29987526 | 0.83 | MEN1 (0.38) | HTR2AHTR2CMEN1KMT2APDCD1LG2 | |
| SCHEMBL13724407 | 0.78 | MAPK1 (0.47) | HTR2AHTR2CMEN1KMT2AMAPK1 | |
| SCHEMBL28892116 | 0.77 | PDCD1LG2 (0.34) | HTR2AHTR2CMEN1KMT2APDCD1LG2 | |
| SCHEMBL17540700 | 0.76 | KMT2A (0.38) | HTR2AHTR2CMEN1KMT2AATM | |
| SCHEMBL24607728 | 0.76 | P2RX7 (0.38) | HTR2AHTR2CMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117279896-A | Amino substituted pyrido ring compounds, preparation method and application thereof | 劲方医药科技(上海)有限公司 | 2023-12-22 | — | — | CN | disclosed |
| WO-2022214044-A1 | AMINE-SUBSTITUTED PYRIDINE FUSED RING COMPOUNDS, PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2022-10-13 | — | — | WO | disclosed |