Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30002457 | 0.87 | HTR6 (0.51) | HTR6KMT2ATSHRPOLBL3MBTL1 | |
| SCHEMBL28892452 | 0.87 | HTR6 (0.51) | HTR6MEN1KMT2ATSHRPOLB | |
| SCHEMBL30002820 | 0.85 | HTR6 (0.49) | HTR6MAPTALDH1A1LMNAHPGD | |
| SCHEMBL30002912 | 0.85 | HTR6 (0.49) | HTR6MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL28892904 | 0.85 | HTR6 (0.52) | HTR6KMT2AALDH1A1LMNATSHR | |
| SCHEMBL30002435 | 0.85 | HTR6 (0.53) | HTR6POLBPKMFABP4 | |
| SCHEMBL30002530 | 0.82 | HTR6 (0.48) | HTR6ALDH1A1LMNATSHRPOLB | |
| SCHEMBL28246141 | 0.81 | HTR6 (0.55) | HTR6HTTMAPTNPSR1RAPGEF4 | |
| SCHEMBL28892345 | 0.80 | MEN1 (0.40) | HTR6HTTMAPTNPSR1RAPGEF4 | |
| SCHEMBL30003158 | 0.79 | HTR6 (0.51) | HTR6ALDH1A1LMNAPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232144-B | Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |