Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | TDO2 | P48775 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28892236 | 0.91 | KMT2A (0.48) | ALDH1A1MAPTKMT2AL3MBTL1LMNA | |
| SCHEMBL30002706 | 0.86 | KMT2A (0.39) | ALDH1A1MAPTKMT2AL3MBTL1LMNA | |
| SCHEMBL28892693 | 0.86 | KMT2A (0.39) | ALDH1A1MAPTKMT2AL3MBTL1LMNA | |
| SCHEMBL28892388 | 0.85 | ALDH1A1 (0.46) | ALDH1A1MAPTKMT2AL3MBTL1LMNA | |
| SCHEMBL28892922 | 0.82 | ALDH1A1 (0.43) | ALDH1A1MAPTKMT2AL3MBTL1LMNA | |
| SCHEMBL30002047 | 0.82 | ALDH1A1 (0.43) | ALDH1A1MAPTKMT2AL3MBTL1LMNA | |
| SCHEMBL30002712 | 0.81 | NSD2 (0.47) | MAPTL3MBTL1KDM4ECASP6TDP1 | |
| SCHEMBL28959473 | 0.81 | NSD2 (0.47) | MAPTL3MBTL1KDM4ECASP6TDP1 | |
| SCHEMBL28959464 | 0.81 | L3MBTL1 (0.40) | ALDH1A1MAPTKMT2AL3MBTL1LMNA | |
| SCHEMBL30003416 | 0.81 | KMT2A (0.50) | ALDH1A1MAPTKMT2AL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232144-B | Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |