Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768577 | 0.76 | NQO2 (0.46) | KDM4EMEN1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL28892605 | 0.76 | ELANE (0.49) | ELANEF2RL3 | |
| SCHEMBL31213014 | 0.73 | NQO2 (0.43) | KDM4EMEN1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL5340379 | 0.72 | KDM4E (0.44) | CNR2KDM4EALDH1A1HPGD | |
| SCHEMBL10852711 | 0.71 | SMN1; SMN2 (0.46) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL5337672 | 0.70 | PTPN1 (0.43) | KDM4EMEN1ALDH1A1CYP2C9HPGD | |
| SCHEMBL9756985 | 0.70 | PLK1 (0.46) | ELANEKDM4EALDH1A1CYP1A2HPGD | |
| SCHEMBL5341017 | 0.70 | F2RL3 (0.39) | KDM4EALDH1A1HPGDF2RL3 | |
| SCHEMBL9381240 | 0.68 | ELANE (0.34) | ELANE | |
| SCHEMBL4584082 | 0.68 | ADA (0.47) | KDM4EMEN1ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232144-B | Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |