Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 7/20 | 0.43 |
| ▸ | UTRN | P46939 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.39 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.37 |
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332553 | 0.84 | CEPT1 (0.51) | PTPN1UTRNCHRNB4CHRNA3CHRNA7 | |
| SCHEMBL5335547 | 0.81 | PTPN1 (0.41) | PTPN1UTRNCHRNB4CHRNA3CHRNA7 | |
| SCHEMBL5340643 | 0.80 | F2RL3 (0.38) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL10852711 | 0.79 | SMN1; SMN2 (0.46) | UTRNKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL4584082 | 0.78 | ADA (0.47) | PTPN1UTRNKDM4EALDH1A1HPGD | |
| SCHEMBL5341017 | 0.77 | F2RL3 (0.39) | KDM4EALDH1A1MAPTHPGDNPC1 | |
| SCHEMBL18935867 | 0.74 | PTPN1 (0.42) | PTPN1UTRNKDM4EALDH1A1HPGD | |
| SCHEMBL5340379 | 0.72 | KDM4E (0.44) | KDM4EALDH1A1MAPTHPGDNPC1 | |
| SCHEMBL2108792 | 0.71 | TOP2A (0.52) | PTPN1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL28892178 | 0.70 | ELANE (0.39) | KDM4EALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262301-B1 | Zinc-chelating ratiometric fluorescent probes and related methods | NORTHWESTERN UNIVERSITY (US) | 2007-08-28 | — | — | US | disclosed |
| US-7105680-B1 | Zinc-chelating ratiometric fluorescent probes and related methods | NORTHWESTERN UNIVERSITY (US) | 2006-09-12 | — | — | US | disclosed |