SCHEMBL2889226

SCHEMBL2889226

CN(c1ccc2c(c1)OC(C)(C)C(O)C2NC(=O)OCCc1ccccc1)S(C)(=O)=O

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KCNE1 P15382 3/20 0.41
KCNQ1 P51787 3/20 0.41
KCNA5 P22460 6/20 0.39
NAAA Q02083 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2888951 0.90 NAAA (0.40) KCNA5NAAA
SCHEMBL2891258 0.85 KCNE1 (0.39) KCNE1KCNQ1KCNA5NAAA
SCHEMBL2889177 0.84 KCNA5 (0.40) KCNA5NAAA
SCHEMBL2889180 0.84 KCNA5 (0.40) KCNA5NAAA
SCHEMBL2891650 0.83 KCNA5 (0.45) KCNE1KCNQ1KCNA5
Hydrochloric Acid SCHEMBL2889246 0.83 KCNA5 (0.45) KCNE1KCNQ1KCNA5
SCHEMBL2883791 0.82 NAAA (0.41) KCNA5NAAA
SCHEMBL2891502 0.82 NAAA (0.42) KCNA5NAAA
SCHEMBL2891660 0.81 NAAA (0.41) KCNA5NAAA
SCHEMBL2891153 0.80 NAAA (0.40) KCNA5NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7781483-B2 Benzopyran compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2010-08-24 US disclosed
US-20070299130-A1 Benzopyran Compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2007-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070299130-A1 Benzopyran Compound NR0B1, CYP2B6, RYR2 KCNE1 166/4885KCNQ1 565/4885KCNA5 69/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.