Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 3/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30002555 | 1.00 | PIK3CB (0.41) | PIK3CBPIK3CDPIK3CAPIK3CGALDH1A1 | |
| SCHEMBL28892454 | 0.89 | POLB (0.50) | PIK3CBALDH1A1GAAPOLBNR3C1 | |
| SCHEMBL28892708 | 0.84 | ALDH1A1 (0.39) | ALDH1A1GAAPOLBRAB9ASMN1; SMN2 | |
| SCHEMBL28892731 | 0.83 | POLB (0.41) | PIK3CBPIK3CDPIK3CAPIK3CGPOLB | |
| SCHEMBL28892486 | 0.82 | ALDH1A1 (0.43) | ALDH1A1GAAPOLBP2RX7SMN1; SMN2 | |
| SCHEMBL16896763 | 0.71 | ACHE (0.42) | ALDH1A1GAASMN1; SMN2MEN1HTT | |
| SCHEMBL30002695 | 0.71 | POLB (0.52) | PIK3CBALDH1A1GAAPOLBNR3C1 | |
| SCHEMBL28892515 | 0.71 | POLB (0.52) | PIK3CBALDH1A1GAAPOLBNR3C1 | |
| SCHEMBL8951518 | 0.70 | KCNJ1 (0.45) | ALDH1A1GAAPOLBRAB9ASMN1; SMN2 | |
| SCHEMBL16896736 | 0.69 | DRD4 (0.42) | ALDH1A1POLBRAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232144-B | Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |