SCHEMBL2889349

SCHEMBL2889349

Cc1cc(Cn2nc(C(F)(F)F)n(CC(F)(F)F)c2=O)ccc1N1C(=O)c2cccc(I)c2C1=O

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
AVPR2 P30518 2/20 0.33
AVPR1A P37288 2/20 0.33
LMNA P02545 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
GRM1 Q13255 7/20 0.32
GRM4 Q14833 6/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2889755 0.94 LMNA (0.33) LMNASMN1; SMN2GRM1GRM4
SCHEMBL2892588 0.85 GRM4 (0.37) LMNASMN1; SMN2GRM1GRM4
SCHEMBL1849927 0.83 LMNA (0.34) LMNASMN1; SMN2GRM1GRM4
SCHEMBL1835277 0.80 GRIA2 (0.39) LMNASMN1; SMN2GRM1GRM4
SCHEMBL2889539 0.79 LMNA (0.33) LMNASMN1; SMN2GRM1GRM4
SCHEMBL2889762 0.78 LMNA (0.34) LMNASMN1; SMN2GRM1GRM4
SCHEMBL2889323 0.78 LMNA (0.33) LMNASMN1; SMN2GRM1GRM4
SCHEMBL5906111 0.77 GRM1 (0.33) LMNASMN1; SMN2GRM1GRM4
SCHEMBL5906073 0.77 PPARG (0.37) GRM1GRM4
SCHEMBL2889814 0.76 LMNA (0.33) LMNASMN1; SMN2GRM1GRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7674807-B2 Heterocycle-substituted n-phenyl-phthalamide derivatives, related compounds and their use as insecticides BAYER CROPSCIENCE AG (DE) 2010-03-09 US disclosed
EP-1727804-B1 N1 - ((PYRAZOL-1-YMETHYL) -2-METHYLPHENYL)- PHATALAMIDE DERIVATIVES AND RELATED COMPOUNDS INSECTICIDES BAYER CROPSCIENCE AG (DE) 2009-11-04 EP disclosed
US-20070299085-A1 N1-((Pyrazol-1-Ymethyl)-2-Methylphenyl)-Phatalamide Derivatives And Related Compounds Insecticides BAYER CROPSCIENCE AG (DE) 2007-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070299085-A1 N1-((Pyrazol-1-Ymethyl)-2-Methylphenyl)-Phatalamide Derivatives And Related Compounds Insecticides CHRM1, KCNH1, DDT AVPR2 2385/4885AVPR1A 2009/4885LMNA 1631/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.