Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29961843 | 1.00 | MAOB (0.56) | MAOBABCB1CYP4F2CYP4A11BCHE | |
| SCHEMBL13332739 | 0.88 | MAOB (0.70) | MAOBABCB1BCHEMRGPRX4 | |
| SCHEMBL6035513 | 0.87 | MAOB (0.65) | MAOBABCB1CYP4F2CYP4A11BCHE | |
| SCHEMBL23718 | 0.85 | MAOB (0.62) | MAOBABCB1CYP4F2CYP4A11BCHE | |
| SCHEMBL24951300 | 0.84 | MAOB (0.46) | MAOBABCB1 | |
| SCHEMBL16687445 | 0.81 | ENPP2 (0.56) | MAOBSMN1; SMN2MRGPRX4TP53PKM | |
| SCHEMBL16687446 | 0.81 | ENPP2 (0.58) | MAOBSMN1; SMN2MRGPRX4TSHRRAB9A | |
| SCHEMBL3271153 | 0.80 | CYP4F2 (0.61) | MAOBCYP4F2CYP4A11BCHESMN1; SMN2 | |
| SCHEMBL31139315 | 0.80 | MAOB (0.53) | MAOBABCB1CYP4F2CYP4A11BCHE | |
| SCHEMBL15761339 | 0.80 | APP (0.61) | MAOBCYP4F2CYP4A11BCHESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115368239-B | Synthesis and pharmaceutical application of cinnamate derivative | 南开大学 | 2024-04-26 | — | — | CN | disclosed |
| CN-115368239-A | Synthesis of cinnamate derivative and pharmaceutical application thereof | 南开大学 | 2022-11-22 | — | — | CN | disclosed |