Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.70 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.59 |
| ▸ | APP | P05067 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 2/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23718 | 0.93 | MAOB (0.62) | MAOBABCB1APPBCHEMRGPRX4 | |
| SCHEMBL28893583 | 0.88 | MAOB (0.56) | MAOBABCB1BCHEMRGPRX4 | |
| SCHEMBL29961843 | 0.88 | MAOB (0.56) | MAOBABCB1BCHEMRGPRX4 | |
| SCHEMBL13263642 | 0.86 | MAOB (0.79) | MAOBABCB1BCHEMRGPRX4 | |
| SCHEMBL23906959 | 0.86 | MAOB (0.79) | MAOBABCB1APPBCHEMRGPRX4 | |
| SCHEMBL13703986 | 0.85 | MAOB (0.67) | MAOBABCB1APPBCHE | |
| SCHEMBL16098550 | 0.85 | ALDH1A1 (0.55) | MAOBABCB1APP | |
| SCHEMBL28987646 | 0.85 | LCK (0.61) | MAOBABCB1APP | |
| Benzylphenylether SCHEMBL28164613 | 0.83 | MAOB (0.75) | MAOBABCB1APPBCHEMRGPRX4 | |
| SCHEMBL15761339 | 0.83 | APP (0.61) | MAOBAPPBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100160305-A1 | 3, 4, 5 - Substituted Piperidine Compounds | NOVARTIS AG (CH) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160305-A1 | 3, 4, 5 - Substituted Piperidine Compounds | REN, ACE, PIGO | MAOB 416/4885ABCB1 999/4885APP 1283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.