Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.54 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.54 |
| ▸ | CDK4 | P11802 | 1/20 | 0.54 |
| ▸ | CCND1 | P24385 | 1/20 | 0.54 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.54 |
| ▸ | CDK2 | P24941 | 1/20 | 0.54 |
| ▸ | CDK9 | P50750 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.49 |
| ▸ | MEN1 | O00255 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28893888 | 1.00 | CCNT1 (0.54) | CCNT1CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL30681210 | 1.00 | CCNT1 (0.54) | CCNT1CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL30681211 | 1.00 | CCNT1 (0.54) | CCNT1CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL1405487 | 0.83 | TSHR (0.67) | CCNT1CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL1405486 | 0.83 | TSHR (0.67) | CCNT1CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL8606801 | 0.83 | RAB9A (0.53) | CCNE2CCNE1CDK2NPC1RAB9A | |
| SCHEMBL8990181 | 0.83 | RAB9A (0.53) | CCNE2CCNE1CDK2NPC1RAB9A | |
| SCHEMBL1405402 | 0.82 | NPC1 (0.65) | CCNT1CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL1405403 | 0.82 | NPC1 (0.65) | CCNT1CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL11595284 | 0.81 | ALDH1A1 (0.70) | CCNT1CCNE2CDK4CCND1CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111217722-B | Azo aryl urea derivative, and preparation method and application thereof | 华东理工大学 | 2024-01-02 | — | — | CN | disclosed |
| CN-111217722-A | Azo aryl urea derivative and preparation method and application thereof | 华东理工大学 | 2020-06-02 | — | — | CN | disclosed |