Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | STAT1 | P42224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28894119 | 0.85 | KMT2A (0.50) | MAPTSMN1; SMN2MEN1KMT2ACYP2C9 | |
| SCHEMBL23951418 | 0.81 | KMT2A (0.44) | MAPTSMN1; SMN2MEN1KMT2ACYP2C9 | |
| SCHEMBL23951524 | 0.80 | GAA (0.47) | MAPTSMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL12128393 | 0.75 | HTT (0.47) | MAPTSMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL2049442 | 0.72 | MEN1 (0.55) | SMN1; SMN2MEN1KMT2ATSHRLMNA | |
| SCHEMBL23649472 | 0.71 | GAA (0.66) | MAPTSMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL31598915 | 0.71 | MEN1 (0.46) | MAPTSMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL25360339 | 0.70 | MEN1 (0.37) | SMN1; SMN2MEN1KMT2AHTTGAA | |
| SCHEMBL959784 | 0.70 | MEN1 (0.37) | SMN1; SMN2MEN1KMT2AHTTGAA | |
| SCHEMBL535681 | 0.70 | HTT (0.36) | SMN1; SMN2MEN1KMT2AHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115209952-A | Substituted pyrazolopyrimidines and use thereof | 维基分析有限公司 | 2022-10-18 | — | — | CN | disclosed |