SCHEMBL535681

SCHEMBL535681

CN(C)S(=O)(=O)n1ccc(Br)n1

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.33
MEN1 O00255 4/20 0.33
KMT2A Q03164 4/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TSHR P16473 1/20 0.32
KDM4E B2RXH2 2/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12128393 0.78 HTT (0.47) HTTSMN1; SMN2MEN1KMT2ANPSR1
SCHEMBL959784 0.77 MEN1 (0.37) HTTSMN1; SMN2MEN1KMT2ANPSR1
SCHEMBL25360339 0.77 MEN1 (0.37) HTTSMN1; SMN2MEN1KMT2ANPSR1
SCHEMBL2158360 0.74 HTT (0.34) HTTSMN1; SMN2MEN1KMT2ANPSR1
SCHEMBL16125119 0.74 SORD (0.37) HTTSMN1; SMN2MEN1KMT2ANPSR1
SCHEMBL14901206 0.74 HTT (0.34) HTTSMN1; SMN2MEN1KMT2ANPSR1
SCHEMBL3024635 0.74 SMN1; SMN2 (0.35) HTTSMN1; SMN2MEN1KMT2ANPSR1
SCHEMBL877521 0.73 CRBN (0.35) HTTMEN1KMT2ANPSR1
SCHEMBL16125118 0.73 HTT (0.33) HTTSMN1; SMN2MEN1KMT2ANPSR1
SCHEMBL4650978 0.72 SMN1; SMN2 (0.39) HTTSMN1; SMN2MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025217330-A1 CYSTEINE COVALENT MODIFIERS OF AKT1 AND USES THEREOF TERREMOTO BIOSCIENCES, INC. (US) 2025-10-16 WO disclosed
US-9445593-B1 Arthropodicidal anthranilamides E I DU PONT DE NEMOURS AND COMPANY (US) 2016-09-20 US disclosed
US-20160255835-A1 ARTHROPODICIDAL ANTHRANILAMIDES FMC CORPORATION 2016-09-08 US disclosed
US-9173400-B2 Anthranilamide arthropodicide treatment E I DU PONT DE NEMOURS AND COMPANY (US) 2015-11-03 US disclosed
US-9161540-B2 Cyano anthranilamide insecticides E I DU PONT DE NEMOURS AND COMPANY (US) 2015-10-20 US disclosed
US-9113630-B2 Method of controlling particular insect pests by applying anthranilamide compounds E I DU PONT DE NEMOURS AND COMPANY (US) 2015-08-25 US disclosed
US-9085578-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2015-07-21 US disclosed
US-9084422-B2 Anthranilamides compositions E I DU PONT DE NEMOURS AND COMPANY (US) 2015-07-21 US disclosed
US-9078437-B2 Arthropodicidal anthranilamides E I DU PONT DE NEMOURS AND COMPANY (US) 2015-07-14 US disclosed
US-9049861-B2 Arthropodicidal anthranilamides E I DU PONT DE NEMOURS AND COMPANY (US) 2015-06-09 US disclosed
WO-2004067528-A1 CYANO ANTHRANILAMIDE INSECTICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-08-12 WO disclosed
EP-1427285-A1 ANTHRANILAMIDE ARTHROPODICIDE TREATMENT E. I. du Pont de Nemours and Company (US) 2004-06-16 EP disclosed
EP-1416796-A1 METHOD FOR CONTROLLING PARTICULAR INSECT PESTS BY APPLYING ANTHRANILAMIDE COMPOUNDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-05-12 EP disclosed
EP-1416797-A1 ARTHROPODICIDAL ANTHRANILAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-05-12 EP disclosed
WO-2004011447-A2 METHOD FOR PREPARING FUSED OXAZINONES FROM ORTHO-AMINO AROMATIC CARBOXYLIC ACID AND A CARBOXYLIC ACID IN THE PRESENCE OF A SULFONYL CHLORIDE AND PYRIDINE E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-02-05 WO disclosed
WO-2003106427-A2 PYRAZOLECARBOXAMIDE INSECTICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-12-24 WO disclosed
WO-2003062226-A1 QUINAZOLINE(DI) ONES FOR INVERTEBRATE PEST CONTROL E. I. DU PONT DE NEMOURS AND COMPANY (US) 2003-07-31 WO disclosed
WO-2003024222-A1 ANTHRANILAMIDE ARTHROPODICIDE TREATMENT E. I. DU PONT DE NEMOURS AND COMPANY (US) 2003-03-27 WO disclosed
WO-2003015518-A1 METHOD FOR CONTROLLING PARTICULAR INSECT PESTS BY APPLYING ANTHRANILAMIDE COMPOUNDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-02-27 WO disclosed
WO-2003015519-A1 ARTHROPODICIDAL ANTHRANILAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-02-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160255835-A1 ARTHROPODICIDAL ANTHRANILAMIDES ANTXR2, NIT2, NAAA HTT 3422/4885SMN1; SMN2 2247/4885MEN1 2273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.