Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | TNF | P01375 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12128393 | 0.78 | HTT (0.47) | MEN1KMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL25360339 | 0.77 | MEN1 (0.37) | MEN1KMT2AHTTSMN1; SMN2NPSR1 | |
| SCHEMBL535681 | 0.77 | HTT (0.36) | MEN1KMT2AHTTSMN1; SMN2NPSR1 | |
| SCHEMBL16125118 | 0.77 | HTT (0.33) | MEN1KMT2AHTTSMN1; SMN2NPSR1 | |
| SCHEMBL3024635 | 0.74 | SMN1; SMN2 (0.35) | MEN1KMT2AHTTSMN1; SMN2NPSR1 | |
| SCHEMBL16125119 | 0.74 | SORD (0.37) | MEN1KMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL2158360 | 0.74 | HTT (0.34) | MEN1KMT2AHTTSMN1; SMN2NPSR1 | |
| SCHEMBL14901206 | 0.74 | HTT (0.34) | MEN1KMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL877521 | 0.73 | CRBN (0.35) | MEN1KMT2AHTTALDH1A1L3MBTL1 | |
| SCHEMBL4650978 | 0.72 | SMN1; SMN2 (0.39) | MEN1KMT2AHTTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4562015-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | Cedilla Therapeutics, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| US-20240352037-A1 | HETEROAROMATIC MACROCYCLIC ETHER CHEMOTHERAPEUTIC AGENTS | NUVALENT, INC. | 2024-10-24 | — | — | US | disclosed |
| US-12054498-B2 | Heteroaromatic macrocyclic ether chemotherapeutic agents | NUVALENT, INC. (US) | 2024-08-06 | — | — | US | disclosed |
| WO-2024026481-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |
| US-20230107663-A1 | HETEROAROMATIC MACROCYCLIC ETHER CHEMOTHERAPEUTIC AGENTS | NUVALENT, INC. | 2023-04-06 | — | — | US | disclosed |
| EP-4146626-A2 | HETEROAROMATIC MACROCYCLIC ETHER CHEMOTHERAPEUTIC AGENTS | Nuvalent, Inc. (US) | 2023-03-15 | — | — | EP | disclosed |
| US-11542278-B1 | Heteroaromatic macrocyclic ether chemotherapeutic agents | NUVALENT, INC. (US) | 2023-01-03 | — | — | US | disclosed |
| WO-2021226208-A2 | HETEROAROMATIC MACROCYCLIC ETHER CHEMOTHERAPEUTIC AGENTS | NUVALENT, INC. (US) | 2021-11-11 | — | — | WO | disclosed |
| US-10647731-B2 | Thiazolopyrimidinones and methods of use thereof | GENENTECH, INC. (US) | 2020-05-12 | — | — | US | disclosed |
| US-20180282298-A1 | PROCESS FOR THE PREPARATION OF THE 3-(3-CHLORO-1H-PYRAZOL-1-YL)PYRIDINE | DOW AGROSCIENCES LLC (US) | 2018-10-04 | — | — | US | disclosed |
| US-20040198984-A1 | 1-(3-halopyrid-2-yl)-3-substituted-5-((2,4-substituted-6-aminocarbonyl)phenylaminocarbonyl) pyrazoles insecticides | FMC CORPORATION | 2004-10-07 | — | — | US | disclosed |
| WO-2004067528-A1 | CYANO ANTHRANILAMIDE INSECTICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-08-12 | — | — | WO | disclosed |
| US-20040102324-A1 | Heterocyclic diamide invertebrate pest control agents | E.I. DU PONT DE NEMOURS AND COMPANY | 2004-05-27 | — | — | US | disclosed |
| EP-1416797-A1 | ARTHROPODICIDAL ANTHRANILAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-05-12 | — | — | EP | disclosed |
| EP-1416796-A1 | METHOD FOR CONTROLLING PARTICULAR INSECT PESTS BY APPLYING ANTHRANILAMIDE COMPOUNDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-05-12 | — | — | EP | disclosed |
| WO-2004011447-A2 | METHOD FOR PREPARING FUSED OXAZINONES FROM ORTHO-AMINO AROMATIC CARBOXYLIC ACID AND A CARBOXYLIC ACID IN THE PRESENCE OF A SULFONYL CHLORIDE AND PYRIDINE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-02-05 | — | — | WO | disclosed |
| EP-1373210-A1 | HETEROCYCLIC DIAMIDE INVERTEBRATE PEST CONTROL AGENTS | E. I. du Pont de Nemours and Company (US) | 2004-01-02 | — | — | EP | disclosed |
| WO-2003015518-A1 | METHOD FOR CONTROLLING PARTICULAR INSECT PESTS BY APPLYING ANTHRANILAMIDE COMPOUNDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-02-27 | — | — | WO | disclosed |
| WO-2003015519-A1 | ARTHROPODICIDAL ANTHRANILAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-02-27 | — | — | WO | disclosed |
| WO-2002070483-A1 | HETEROCYCLIC DIAMIDE INVERTEBRATE PEST CONTROL AGENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180282298-A1 | PROCESS FOR THE PREPARATION OF THE 3-(3-CHLORO-1H-PYRAZOL-1-YL)PYRIDINE | CPS1, CBR3, PDXK | MEN1 2534/4885KMT2A 1547/4885HTT 2218/4885 |
| US-10647731-B2 | Thiazolopyrimidinones and methods of use thereof | TPMT, THPO, CYP11B2 | MEN1 1268/4885KMT2A 4461/4885HTT 657/4885 |
| US-20240352037-A1 | HETEROAROMATIC MACROCYCLIC ETHER CHEMOTHERAPEUTIC AGENTS | ABCB1, CYP2C8, PAICS | MEN1 1607/4885KMT2A 2069/4885HTT 391/4885 |
| US-20040198984-A1 | 1-(3-halopyrid-2-yl)-3-substituted-5-((2,4-substituted-6-aminocarbonyl)phenylaminocarbonyl) pyrazoles insecticides | CYP4B1, CYP1B1, CYP2E1 | MEN1 4107/4885KMT2A 2856/4885HTT 3876/4885 |
| US-20040102324-A1 | Heterocyclic diamide invertebrate pest control agents | DDT, DBF4, DDC | MEN1 1735/4885KMT2A 1777/4885HTT 2716/4885 |
| US-12054498-B2 | Heteroaromatic macrocyclic ether chemotherapeutic agents | CYP2C8, ABCB1, CYP3A43 | MEN1 1170/4885KMT2A 2154/4885HTT 1190/4885 |
| US-11542278-B1 | Heteroaromatic macrocyclic ether chemotherapeutic agents | CYP2C8, ABCB1, CYP3A43 | MEN1 1170/4885KMT2A 2154/4885HTT 1190/4885 |
| US-20230107663-A1 | HETEROAROMATIC MACROCYCLIC ETHER CHEMOTHERAPEUTIC AGENTS | ABCB1, CYP2C8, PAICS | MEN1 1607/4885KMT2A 2069/4885HTT 391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.