SCHEMBL28894199

SCHEMBL28894199

C=CC(=O)OC(CCCCCCCCCCC)[Si](OC)(OC)OC

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.41
HPGD P15428 1/20 0.41
ZDHHC7 Q9NXF8 1/20 0.38
ABCB1 P08183 1/20 0.37
THRB P10828 2/20 0.36
THRA P10827 1/20 0.36
ZDHHC20 Q5W0Z9 2/20 0.36
ZDHHC2 Q9UIJ5 2/20 0.36
GPR84 Q9NQS5 4/20 0.35
FFAR1 O14842 1/20 0.35
MAPT P10636 1/20 0.34
LCK P06239 1/20 0.34
PPARD Q03181 1/20 0.34
FAAH O00519 3/20 0.34
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28894229 1.00 TSHR (0.41) TSHRHPGDZDHHC7ABCB1THRB
SCHEMBL20336761 1.00 TSHR (0.41) TSHRHPGDZDHHC7ABCB1THRB
SCHEMBL1974554 1.00 TSHR (0.41) TSHRHPGDZDHHC7ABCB1THRB
SCHEMBL9947913 1.00 TSHR (0.41) TSHRHPGDZDHHC7ABCB1THRB
SCHEMBL9947807 0.98 TSHR (0.42) TSHRHPGDZDHHC7ABCB1THRB
SCHEMBL9947745 0.94 TSHR (0.46) TSHRHPGDZDHHC7ABCB1THRB
SCHEMBL3905874 0.87 TSHR (0.38) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL29005322 0.87 TSHR (0.40) TSHRHPGDZDHHC7ABCB1THRB
SCHEMBL21224467 0.87 TSHR (0.40) TSHRHPGDZDHHC7ABCB1THRB
SCHEMBL4202060 0.87 TSHR (0.40) TSHRHPGDZDHHC7ABCB1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4725470-A1 CURABLE DENTAL COMPOSITION Kuraray Noritake Dental Inc. (JP) 2026-04-15 EP disclosed
EP-4696297-A1 COMPOSITE MATERIAL FOR DENTAL CUTTING Yamakin Co.,Ltd. (JP) 2026-02-18 EP disclosed
EP-4563609-A1 PHOTOCURABLE COMPOSITION, CURED PRODUCT OF SAME, AND COATED ARTICLE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-06-04 EP disclosed
US-20250032366-A1 DENTAL CURABLE COMPOSITION KURARAY NORITAKE DENTAL INC. (JP) 2025-01-30 US disclosed
US-20250009607-A1 DENTAL COMPOSITION AND METHOD OF PRODUCTION THEREOF, AND SURFACE-TREATED FILLER FOR DENTAL USE KURARAY NORITAKE DENTAL INC. (JP) 2025-01-09 US disclosed
WO-2024253204-A1 CURABLE DENTAL COMPOSITION クラレノリタケデンタル株式会社 2024-12-12 WO disclosed
EP-4464301-A1 DENTAL COMPOSITION, METHOD FOR MANUFACTURING SAME, AND DENTAL SURFACE-TREATED FILLER Kuraray Noritake Dental Inc. (JP) 2024-11-20 EP disclosed
WO-2024214817-A1 COMPOSITE MATERIAL FOR DENTAL CUTTING YAMAKIN株式会社 2024-10-17 WO disclosed
EP-4445891-A1 DENTAL CURABLE COMPOSITION Kuraray Noritake Dental Inc. (JP) 2024-10-16 EP disclosed
CN-111902206-B Hollow particles, method for producing same, and use thereof 积水化成品工业株式会社 2023-03-24 CN disclosed
CN-115361869-A Adhesive tape containing pesticide 米琪邦株式会社 2022-11-18 CN disclosed
CN-109890344-B Subpackaged dental adhesive 可乐丽则武齿科株式会社 2022-02-22 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250032366-A1 DENTAL CURABLE COMPOSITION H1-0, COL1A1, CHAF1B TSHR 4352/4885HPGD 2520/4885ZDHHC7 4414/4885
US-20250009607-A1 DENTAL COMPOSITION AND METHOD OF PRODUCTION THEREOF, AND SURFACE-TREATED FILLER FOR DENTAL USE CAD, SEM1, CAPZA1 TSHR 3083/4885HPGD 1522/4885ZDHHC7 3425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.