Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27032963 | 0.80 | TDP1 (0.39) | TDP1TSHRCYP3A4 | |
| SCHEMBL27131685 | 0.80 | TDP1 (0.39) | TDP1TSHRCYP3A4 | |
| SCHEMBL10912094 | 0.77 | ALDH1A1 (0.40) | SMN1; SMN2MAPTMEN1KMT2ACHRNB2 | |
| SCHEMBL25416858 | 0.77 | ALDH1A1 (0.40) | SMN1; SMN2MAPTMEN1KMT2ACHRNB2 | |
| SCHEMBL30564475 | 0.77 | TSHR (0.38) | TDP1TSHRCYP3A4 | |
| SCHEMBL27705276 | 0.76 | TSHR (0.46) | TDP1TSHRCYP3A4PKMSMN1; SMN2 | |
| SCHEMBL797852 | 0.74 | — | — | |
| SCHEMBL23879167 | 0.73 | CASP1 (0.33) | TDP1TSHRCYP3A4 | |
| SCHEMBL7603108 | 0.73 | TDP1 (0.43) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL4625216 | 0.73 | TDP1 (0.43) | TDP1TSHRCYP3A4SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115362162-A | Heteroaryl compounds for the treatment of complement factor D mediated disorders | 艾其林医药公司 | 2022-11-18 | — | — | CN | disclosed |