SCHEMBL28895274

SCHEMBL28895274

C=CC(=O)N(C)C(=O)CN

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.32
TSHR P16473 2/20 0.32
FGFR4 P22455 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8528460 0.79 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL5699611 0.77 ALDH1A1 (0.44) ALDH1A1TSHRFGFR4
SCHEMBL28621037 0.76 ALDH1A1 (0.35) ALDH1A1TSHRFGFR4
SCHEMBL8529532 0.74 HSD17B10 (0.30) ALDH1A1TSHR
SCHEMBL3701495 0.74 ALDH1A1 (0.34) ALDH1A1TSHR
SCHEMBL203010 0.73
SCHEMBL28542660 0.72 TSHR (0.31) TSHR
Ethylenediamine SCHEMBL515314 0.71 TSHR (0.35) ALDH1A1TSHRFGFR4
SCHEMBL3360475 0.71
SCHEMBL8962640 0.71 ALDH1A1 (0.35) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114316136-B Hydrogen bond enhanced hydrate inhibitor and preparation method thereof 西华师范大学 2023-01-31 CN disclosed
CN-114316136-A Hydrogen bond enhanced hydrate inhibitor and preparation method thereof 西华师范大学 2022-04-12 CN disclosed