Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.60 |
| ▸ | MME | P08473 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 3/20 | 0.47 |
| ▸ | CTSK | P43235 | 3/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | HTR2B | P41595 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2548016 | 0.88 | ATM (0.51) | PIN1ATMCTSSCTSKSCN9A | |
| SCHEMBL2548015 | 0.88 | ATM (0.51) | PIN1ATMCTSSCTSKSCN9A | |
| SCHEMBL4901923 | 0.88 | ATM (0.51) | PIN1ATMCTSSCTSKSCN9A | |
| SCHEMBL5756417 | 0.87 | ATM (0.50) | PIN1ATMCTSSCTSKSCN9A | |
| SCHEMBL27475975 | 0.86 | CTSS (0.62) | PIN1MMEATMCTSSCTSK | |
| SCHEMBL16818 | 0.86 | CTSS (0.62) | PIN1MMEATMCTSSCTSK | |
| SCHEMBL29163526 | 0.86 | FFAR2 (0.54) | PIN1MMEATMFFAR2CTSS | |
| SCHEMBL1519752 | 0.86 | FFAR2 (0.54) | PIN1MMEATMFFAR2CTSS | |
| SCHEMBL31758020 | 0.85 | ATM (0.55) | PIN1ATMCTSSCTSKCTSB | |
| SCHEMBL489490 | 0.84 | ATM (0.70) | ATMCTSSCTSKCYP3A4CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111344281-B | Potassium channel inhibitors substituted benzimidazoles | 阿塞西翁制药公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-111344281-A | Potassium channel inhibitors of substituted benzimidazoles | 阿塞西翁制药公司 | 2020-06-26 | — | — | CN | disclosed |