SCHEMBL28895409

SCHEMBL28895409

CC(=O)OC(C)=O.Cc1cc(C)cc(C)c1

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.59
TSHR P16473 3/20 0.59
TPMT P51580 1/20 0.48
LMNA P02545 2/20 0.42
TDP1 Q9NUW8 2/20 0.41
HSD17B10 Q99714 1/20 0.41
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
CYP3A4 P08684 1/20 0.39
MAPK1 P28482 1/20 0.39
RXRA P19793 1/20 0.38
RXRB P28702 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CNR2 P34972 2/20 0.36
HCAR1 Q9BXC0 1/20 0.36
HPGD P15428 1/20 0.35
ELANE P08246 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28426145 0.83 TPMT (0.50) ALDH1A1TSHRTPMTTDP1MEN1
P-Xylene SCHEMBL9456427 0.82 LMNA (0.61) ALDH1A1TSHRLMNATDP1HSD17B10
Acetic Acid Methyl Ester SCHEMBL28118872 0.82 ALDH1A1 (0.59) ALDH1A1TPMTLMNATDP1MEN1
Acetone SCHEMBL9722029 0.81 TPMT (0.58) ALDH1A1TSHRTPMTLMNATDP1
Acetic Acid SCHEMBL27834373 0.78 TPMT (0.63) ALDH1A1TSHRTPMTMEN1KMT2A
SCHEMBL1331977 0.77
SCHEMBL9866292 0.77
SCHEMBL523 0.77
SCHEMBL1331774 0.77
SCHEMBL1330344 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111362803-A Microchannel reaction process for continuously synthesizing 1-nitro mesitylene 南京大学淮安高新技术研究院 2020-07-03 CN claimed
CN-111362803-A Microchannel reaction process for continuously synthesizing 1-nitro mesitylene 南京大学淮安高新技术研究院 2020-07-03 CN disclosed