Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VEGFA | P15692 | 8/20 | 0.53 |
| ▸ | EPAS1 | Q99814 | 18/20 | 0.51 |
| ▸ | ARNT | P27540 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28425970 | 1.00 | VEGFA (0.53) | VEGFAEPAS1ARNTCYP2C9CYP2C19 | |
| SCHEMBL30136472 | 1.00 | VEGFA (0.53) | VEGFAEPAS1ARNTCYP2C9CYP2C19 | |
| SCHEMBL28425966 | 1.00 | VEGFA (0.53) | VEGFAEPAS1ARNTCYP2C9CYP2C19 | |
| SCHEMBL30136471 | 1.00 | VEGFA (0.53) | VEGFAEPAS1ARNTCYP2C9CYP2C19 | |
| SCHEMBL30136465 | 0.88 | EPAS1 (0.48) | VEGFAEPAS1ARNTCYP2C9CYP2C19 | |
| SCHEMBL28426398 | 0.88 | EPAS1 (0.48) | VEGFAEPAS1ARNTCYP2C9CYP2C19 | |
| SCHEMBL23935869 | 0.80 | VEGFA (0.58) | VEGFAEPAS1ARNTCYP2C9CYP2C19 | |
| SCHEMBL30136473 | 0.80 | EPAS1 (0.78) | VEGFAEPAS1 | |
| SCHEMBL30136495 | 0.80 | EPAS1 (0.78) | VEGFAEPAS1 | |
| SCHEMBL28426265 | 0.80 | EPAS1 (0.78) | VEGFAEPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111303053-A | Cyclopenta [ d ] pyrimidine compound and pharmaceutically acceptable salt, solvate or prodrug thereof and application | 中国海洋大学 | 2020-06-19 | — | — | CN | claimed |
| CN-111303053-B | Cyclopenta [ d ] pyrimidine compound and pharmaceutically acceptable salt, solvate or prodrug thereof and application | 中国海洋大学 | 2023-01-17 | — | — | CN | disclosed |
| CN-111303053-A | Cyclopenta [ d ] pyrimidine compound and pharmaceutically acceptable salt, solvate or prodrug thereof and application | 中国海洋大学 | 2020-06-19 | — | — | CN | disclosed |