Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 8/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 8/20 | 0.36 |
| ▸ | CNR2 | P34972 | 4/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | MTHFD2 | P13995 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28579456 | 0.89 | GRM5 (0.40) | PDCD1CD274CNR2 | |
| SCHEMBL29225581 | 0.85 | HDAC1 (0.31) | — | |
| SCHEMBL23360915 | 0.84 | PDCD1 (0.47) | PDCD1CD274 | |
| Lithium SCHEMBL29716028 | 0.83 | PDCD1 (0.46) | PDCD1CD274 | |
| SCHEMBL28758427 | 0.83 | CNR2 (0.35) | PDCD1CD274CNR2P2RX7DPP4 | |
| SCHEMBL29191201 | 0.82 | ADORA1 (0.46) | CNR2 | |
| SCHEMBL23244377 | 0.79 | CNR2 (0.49) | CNR2P2RX7DPP4DPP8DPP7 | |
| SCHEMBL28595450 | 0.78 | PDCD1 (0.53) | PDCD1CD274 | |
| SCHEMBL28477398 | 0.77 | CNR2 (0.32) | CNR2P2RX7DPP4DPP8DPP7 | |
| SCHEMBL30916147 | 0.76 | CREBBP (0.39) | PDCD1CD274CNR2DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112752756-B | Tetrahydro-imidazo [4,5-c ] pyridine derivatives as PD-L1 immunomodulators | 因赛特公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-110582493-B | Benzoxazole derivatives as immunomodulators | 因赛特公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-116115764-A | Tetrahydroimidazo [4,5-C ] pyridine derivatives as PD-L1 internalization inducers | 因赛特公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-110267953-B | Tetrahydroimidazo [4,5-C ] pyridine derivatives as inducers of PD-L1 internalization | 因赛特公司 | 2022-12-20 | — | — | CN | disclosed |
| CN-109890819-B | Heterocyclic compounds as immunomodulators | 因赛特公司 | 2022-11-22 | — | — | CN | disclosed |