Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 4/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.38 |
| ▸ | BPTF | Q12830 | 1/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28579456 | 0.87 | GRM5 (0.40) | CREBBPBRD4GRM5BAZ2BPIK3R1 | |
| SCHEMBL23611067 | 0.83 | PDCD1 (0.46) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL23374970 | 0.80 | CCR5 (0.42) | CREBBPBRD4GRM5BAZ2BPIK3R1 | |
| SCHEMBL29716001 | 0.78 | PDCD1 (0.41) | ALDH1A1L3MBTL1PIK3R1PIK3CAMEN1 | |
| SCHEMBL30340518 | 0.78 | PDCD1 (0.43) | ALDH1A1L3MBTL1MEN1KMT2AKDM4E | |
| SCHEMBL30703775 | 0.77 | PDCD1 (0.42) | PDCD1CD274DPP4CNR2 | |
| SCHEMBL29933269 | 0.77 | CNR2 (0.43) | PIK3R1PIK3CAPDCD1CD274DPP4 | |
| SCHEMBL29022800 | 0.77 | PDCD1 (0.52) | PDCD1CD274 | |
| SCHEMBL28508015 | 0.77 | DPP4 (0.35) | DPP4 | |
| SCHEMBL30966759 | 0.76 | PDCD1 (0.39) | PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936475-B | Immunomodulator, composition and preparation method thereof | 贝达药业股份有限公司 | 2024-05-10 | — | — | CN | claimed |
| CN-111936475-B | Immunomodulator, composition and preparation method thereof | 贝达药业股份有限公司 | 2024-05-10 | — | — | CN | disclosed |