Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 7/20 | 0.57 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | POLQ | O75417 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30076074 | 1.00 | RORC (0.57) | RORCMRGPRX4NOTUMPPARGKIF11 | |
| SCHEMBL30076077 | 0.93 | RORC (0.55) | RORCMRGPRX4NOTUMPPARGKIF11 | |
| SCHEMBL28895592 | 0.93 | RORC (0.55) | RORCMRGPRX4NOTUMPPARGKIF11 | |
| SCHEMBL19360544 | 0.93 | RORC (0.65) | RORCMRGPRX4NOTUMPPARGKIF11 | |
| SCHEMBL29465606 | 0.93 | RORC (0.65) | RORCMRGPRX4NOTUMPPARGKIF11 | |
| SCHEMBL28797831 | 0.91 | RORC (0.57) | RORCMRGPRX4NOTUMPPARGKIF11 | |
| SCHEMBL29654191 | 0.91 | RORC (0.57) | RORCMRGPRX4NOTUMPPARGKIF11 | |
| SCHEMBL28895701 | 0.89 | RORC (0.51) | RORCMRGPRX4NOTUMPPARGKIF11 | |
| SCHEMBL28895765 | 0.89 | RORC (0.56) | RORCMRGPRX4PPARGEPHX2POLQ | |
| SCHEMBL29654060 | 0.88 | RORC (0.54) | RORCMRGPRX4NOTUMPPARGKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109963836-B | Deuterium atom substituted indole carboxamide derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2022-11-22 | — | — | CN | disclosed |