Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 6/20 | 0.54 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 3/20 | 0.38 |
| ▸ | POLQ | O75417 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28285094 | 1.00 | RORC (0.54) | RORCMRGPRX4KDM4EALDH1A1HPGD | |
| SCHEMBL29654191 | 0.90 | RORC (0.57) | RORCMRGPRX4ALDH1A1KIF11POLQ | |
| SCHEMBL29465606 | 0.90 | RORC (0.65) | RORCMRGPRX4KDM4EKIF11POLQ | |
| SCHEMBL28797831 | 0.90 | RORC (0.57) | RORCMRGPRX4ALDH1A1KIF11POLQ | |
| SCHEMBL19360544 | 0.90 | RORC (0.65) | RORCMRGPRX4KDM4EKIF11POLQ | |
| SCHEMBL28285097 | 0.90 | RORC (0.55) | RORCMRGPRX4KDM4EALDH1A1HPGD | |
| SCHEMBL28895592 | 0.88 | RORC (0.55) | RORCMRGPRX4KIF11POLQEPHX2 | |
| SCHEMBL30076077 | 0.88 | RORC (0.55) | RORCMRGPRX4KIF11POLQEPHX2 | |
| SCHEMBL30076074 | 0.88 | RORC (0.57) | RORCMRGPRX4KDM4EKIF11POLQ | |
| SCHEMBL28895708 | 0.88 | RORC (0.57) | RORCMRGPRX4KDM4EKIF11POLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109485595-B | Hydrophilic group substituted indole formamide derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2022-05-27 | — | — | CN | disclosed |