Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | NAMPT | P43490 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 6/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 6/20 | 0.49 |
| ▸ | DRD3 | P35462 | 4/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6585625 | 0.84 | DRD4 (0.63) | HDAC4NAMPTDRD4SIGMAR1DRD2 | |
| SCHEMBL2395932 | 0.84 | DRD4 (0.67) | HDAC4NAMPTDRD4SIGMAR1DRD2 | |
| SCHEMBL8441289 | 0.82 | KDM4E (0.50) | DRD4SIGMAR1DRD2DRD3HTR1A | |
| SCHEMBL2395803 | 0.81 | LMNA (0.60) | HDAC4NAMPTDRD4SIGMAR1DRD2 | |
| SCHEMBL10287534 | 0.81 | SIGMAR1 (0.71) | HDAC4NAMPTDRD4SIGMAR1DRD2 | |
| SCHEMBL29188191 | 0.81 | DRD4 (0.67) | HDAC4NAMPTDRD4SIGMAR1DRD2 | |
| SCHEMBL2392338 | 0.80 | DRD4 (0.56) | HDAC4NAMPTDRD4SIGMAR1DRD2 | |
| SCHEMBL2395917 | 0.80 | MAPK1 (0.69) | HDAC4NAMPTDRD4SIGMAR1DRD2 | |
| SCHEMBL13959654 | 0.80 | DRD4 (0.56) | HDAC4NAMPTDRD4SIGMAR1DRD2 | |
| SCHEMBL2582694 | 0.80 | HDAC4 (0.58) | HDAC4NAMPTDRD4SIGMAR1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112724070-B | Preparation method of alpha, alpha-diphenyl-4-piperidinemethanol | 南京方生和医药科技有限公司 | 2022-11-25 | — | — | CN | claimed |
| CN-112724070-A | Preparation method of alpha, alpha-diphenyl-4-piperidinemethanol | 南京方生和医药科技有限公司 | 2021-04-30 | — | — | CN | claimed |
| CN-112724070-B | Preparation method of alpha, alpha-diphenyl-4-piperidinemethanol | 南京方生和医药科技有限公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-112724070-B | Preparation method of alpha, alpha-diphenyl-4-piperidinemethanol | 南京方生和医药科技有限公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-112724070-A | Preparation method of alpha, alpha-diphenyl-4-piperidinemethanol | 南京方生和医药科技有限公司 | 2021-04-30 | — | — | CN | disclosed |
| CN-112724070-A | Preparation method of alpha, alpha-diphenyl-4-piperidinemethanol | 南京方生和医药科技有限公司 | 2021-04-30 | — | — | CN | disclosed |