Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 4/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 3/20 | 0.44 |
| ▸ | DRD3 | P35462 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9387391 | 0.80 | CYP2D6 (0.47) | ALDH1A1SIGMAR1DRD2HTR1AHTR2A | |
| SCHEMBL12798134 | 0.78 | SIGMAR1 (0.55) | SIGMAR1DRD2HTR1AHTR2AHTT | |
| SCHEMBL3079800 | 0.77 | MEN1 (0.48) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9074062 | 0.76 | KDM4E (0.54) | ALDH1A1DRD2DRD4DRD3KDM4E | |
| SCHEMBL5778817 | 0.76 | MEN1 (0.56) | ALDH1A1MAPK1MEN1LMNATSHR | |
| SCHEMBL325460 | 0.74 | SIGMAR1 (0.50) | SIGMAR1DRD2HTR1AHTR2AHTT | |
| SCHEMBL1076822 | 0.73 | SIGMAR1 (0.53) | SIGMAR1DRD2HTR1AHTR2AHTT | |
| SCHEMBL2395932 | 0.73 | DRD4 (0.67) | SIGMAR1DRD2HTR1AHTR2AHTT | |
| SCHEMBL8830945 | 0.73 | SIGMAR1 (0.53) | SIGMAR1DRD2HTR1AHTR2AHTT | |
| SCHEMBL15332629 | 0.73 | SIGMAR1 (0.48) | SIGMAR1DRD2HTR1AHTR2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112724070-B | Preparation method of alpha, alpha-diphenyl-4-piperidinemethanol | 南京方生和医药科技有限公司 | 2022-11-25 | — | — | CN | disclosed |