Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.42 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | VCP | P55072 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16720112 | 0.79 | FFAR1 (0.43) | PTPN6PTPN11PTPN22GPR35HAO1 | |
| SCHEMBL16720506 | 0.78 | GPR35 (0.48) | PTPN6PTPN11PTPN22GPR35HAO1 | |
| SCHEMBL16719515 | 0.76 | KDM4E (0.40) | PTPN6PTPN11PTPN22FFAR1CA12 | |
| SCHEMBL16719707 | 0.75 | FFAR1 (0.40) | PTPN6PTPN11PTPN22HAO1FFAR1 | |
| SCHEMBL16720126 | 0.75 | FFAR1 (0.44) | PTPN6PTPN11PTPN22FFAR1DHODH | |
| SCHEMBL27952694 | 0.72 | GRM5 (0.55) | HAO1FFAR1CA12CA1CA2 | |
| SCHEMBL18125291 | 0.71 | FFAR1 (0.37) | PTPN6PTPN11FFAR1CA12CA1 | |
| SCHEMBL16720454 | 0.70 | PARP1 (0.46) | FFAR1DHODHCA12CA1CA2 | |
| SCHEMBL16720280 | 0.69 | G6PD (0.47) | PTPN6PTPN11FFAR1CA12CA1 | |
| SCHEMBL28418395 | 0.69 | FFAR1 (0.46) | PTPN6PTPN11PTPN22HAO1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105934425-B | EBNA1 inhibitors and methods of use thereof | 威斯塔解剖学和生物学研究所 | 2020-08-07 | — | — | CN | disclosed |