Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 8/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | JAK1 | P23458 | 2/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28896609 | 0.85 | KMT2A (0.35) | MAPTKDM4EALDH1A1SMN1; SMN2JAK1 | |
| SCHEMBL29211235 | 0.84 | AAK1 (0.32) | MAPTKDM4ENPSR1AAK1SMN1; SMN2 | |
| SCHEMBL28896426 | 0.82 | PTGER4 (0.38) | MAPTKDM4EALDH1A1SMN1; SMN2PTGER4 | |
| SCHEMBL28896253 | 0.80 | NUDT1 (0.38) | MAPTKDM4EALDH1A1SMN1; SMN2PTGER4 | |
| SCHEMBL28896526 | 0.77 | MAPT (0.30) | MAPTNPSR1 | |
| SCHEMBL28896541 | 0.77 | AAK1 (0.45) | ABCB1MAPTKDM4ENPSR1TDP1 | |
| SCHEMBL28896542 | 0.77 | AAK1 (0.45) | ABCB1MAPTKDM4ENPSR1TDP1 | |
| SCHEMBL1536739 | 0.76 | TSHR (0.45) | MAPTKDM4EALDH1A1SMN1; SMN2PTGER4 | |
| SCHEMBL4393322 | 0.76 | KDM4E (0.41) | MAPTKDM4ENPSR1ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL25312311 | 0.75 | TSHR (0.44) | MAPTKDM4EALDH1A1SMN1; SMN2PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403584-B | 2-thio-2, 3-dihydropyrimidine-4-one derivatives, pharmaceutical compositions, preparation methods and applications thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115403584-A | 2-thio-2, 3-dihydropyrimidine-4-one derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-11-29 | — | — | CN | disclosed |