Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 10/20 | 0.33 |
| ▸ | JAK2 | O60674 | 3/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.33 |
| ▸ | ACACB | O00763 | 3/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28896523 | 0.73 | MPO (0.48) | JAK1JAK2 | |
| SCHEMBL28896661 | 0.71 | CYP4F2 (0.38) | ACACBCYP11B2 | |
| SCHEMBL29211272 | 0.69 | RORC (0.37) | ACACBCYP11B2 | |
| SCHEMBL31752520 | 0.69 | USP2 (0.39) | ACACBCYP11B2 | |
| SCHEMBL28896357 | 0.67 | USP2 (0.37) | ACACBCYP11B2 | |
| SCHEMBL28896246 | 0.66 | ACACB (0.36) | GPR119ACACBCYP11B2 | |
| SCHEMBL28896077 | 0.66 | MPO (0.51) | JAK1JAK2 | |
| SCHEMBL24113337 | 0.65 | USP2 (0.41) | ACACBCYP11B2 | |
| SCHEMBL24012213 | 0.65 | USP2 (0.41) | ACACBCYP11B2 | |
| SCHEMBL29581801 | 0.65 | USP2 (0.41) | ACACBCYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403584-B | 2-thio-2, 3-dihydropyrimidine-4-one derivatives, pharmaceutical compositions, preparation methods and applications thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115403584-A | 2-thio-2, 3-dihydropyrimidine-4-one derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-11-29 | — | — | CN | disclosed |