Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | RGS12 | O14924 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL915218 | 1.00 | LMNA (0.62) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL3055513 | 1.00 | LMNA (0.62) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL1711563 | 1.00 | LMNA (0.62) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL29674753 | 1.00 | LMNA (0.62) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL430516 | 1.00 | LMNA (0.62) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL1417856 | 1.00 | LMNA (0.62) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL5598127 | 0.87 | LMNA (0.56) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL14474285 | 0.87 | LMNA (0.56) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL11602702 | 0.86 | IDO1 (0.54) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| Phosphoric Acid SCHEMBL4954578 | 0.86 | SRC (0.58) | LMNAADRA2CKDM4EADRA2AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107428802-B | Cyclic peptide compounds, their preparation and use | 浙江海正药业股份有限公司 | 2021-09-28 | — | — | CN | disclosed |
| EP-3305405-A1 | MANGAN(III)-MANGAN(IV) MIXED OXIDE CATALYST CONTAINING AN INTERCALATED CATION X FOR AEROBIC OXIDATIVE CLEAVAGE OF 1,2-DIOLS | Centre National De La Recherche Scientifique (FR) | 2018-04-11 | — | — | EP | disclosed |
| CN-107428802-A | Cyclic peptide compounds, their preparation and use | 浙江海正药业股份有限公司 | 2017-12-01 | — | — | CN | disclosed |
| US-9023652-B2 | Organometallic sensor device | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LTD. (GB) | 2015-05-05 | — | — | US | disclosed |
| US-8754234-B2 | Chiral 2-(benzylsulfinyl)thiazole derivatives and 2-[(1H-pyrazol-4-ylmethyl)sulfinyl]thiazole derivatives, processes for their preparation and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2014-06-17 | — | — | US | disclosed |
| US-8513442-B2 | Methods of performing cycloadditions, reaction mixtures, and methods of performing asymmetric catalytic reactions | THE UNIVERSITY OF CHICAGO (US) | 2013-08-20 | — | — | US | disclosed |
| US-20100285602-A1 | ORGANOMETALLIC SENSOR DEVICE | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LTD. (GB) | 2010-11-11 | — | — | US | disclosed |
| US-20100285958-A1 | Chiral 2-(benzylsulfinyl)Thiazole derivatives and 2-[(1H-pyrazol-4-ylmethyl)sulfinyl]thiazole derivatives, processes for their preparation and their use as herbicides and plant growth regulators | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2010-11-11 | — | — | US | disclosed |
| US-20100184999-A1 | Methods of performing cycloadditions, reaction mixtures, and methods of performing asymmetric catalytic reactions | THE UNIVERSITY OF CHICAGO | 2010-07-22 | — | — | US | disclosed |
| EP-1181014-B1 | HETEROCYCLIC CONTAINING BIPHENYL aP2 INHIBITORS AND METHOD | BRISTOL MYERS SQUIBB CO (US) | 2007-05-23 | — | — | EP | disclosed |
| US-20030176746-A1 | Multifunctional catalyst useful in the synthesis of chiral vicinal diols and process for the preparation thereof, and process for the preparation of chiral vicinal diols using said multifunctional catalysts | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-09-18 | — | — | US | disclosed |
| US-20030153794-A1 | Process for the preparation of supported osmates | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH. | 2003-08-14 | — | — | US | disclosed |
| US-20030105367-A1 | Supported osmates, process for preparation thereof, and a process for the preparation of chiral vicinal diols using supported osmate catalyst | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-06-05 | — | — | US | disclosed |
| WO-2003035253-A1 | PROCESS FOR THE PREPARATION OF SUPPORTED OSMATES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-05-01 | — | — | WO | disclosed |
| US-6552234-B1 | Reacting potassium osmate with such as quaternary ammonium divinylbenzene-styrene copolymer | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-04-22 | — | — | US | disclosed |
| US-6548529-B1 | AP2 (adipocyte fatty binding protein); biphenyl-substituted pyrazoles of given formula; treating diabetes and related diseases; mixtures with other antidiabetic agents such as metformin, glyburide, troglitazone and/or insulin | BRISTOL-MYERS SQUIBB COMPANY | 2003-04-15 | — | — | US | disclosed |
| EP-1209142-A1 | Preparation of new layered double hydroxides exchanged with osmate for asymmetric dihydroxylation of olefins to vicinal diols | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2002-05-29 | — | — | EP | disclosed |
| US-6387033-B1 | CIS ISOMERS FOR HYDROXYLATION OF OLEFINS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2002-05-14 | — | — | US | disclosed |
| US-6197994-B1 | PREPARING VICINAL DIOLS BY CATALYTIC ASYMMETRIC DIHYDROXYLATION OF OLEFINS USING SILICA GEL SUPPORTED BIS-CINCHONA ALKALOID DERIVATIVE | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2001-03-06 | — | — | US | disclosed |
| US-5968867-A | REUSABLE CATALYSTS FOR DIHYDROXYLATION OF OLEFINS TO OPTICALLY-ACTIVE VICINAL DIOLS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1999-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100285958-A1 | Chiral 2-(benzylsulfinyl)Thiazole derivatives and 2-[(1H-pyrazol-4-ylmethyl)sulfinyl]thiazole derivatives, processes for their preparation and their use as herbicides and plant growth regulators | STS, SULT2A1, SLTM | LMNA 4704/4885ADRA2C 1902/4885KDM4E 1930/4885 |
| US-20100184999-A1 | Methods of performing cycloadditions, reaction mixtures, and methods of performing asymmetric catalytic reactions | DCXR, POR, COASY | LMNA 4300/4885ADRA2C 1392/4885KDM4E 4614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.