Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.65 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | GLA | P06280 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.65 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23052579 | 0.94 | MEN1 (0.60) | KMT2AMEN1MAPTNPSR1L3MBTL1 | |
| SCHEMBL23052500 | 0.94 | KMT2A (0.65) | KMT2AMEN1MAPTNPSR1L3MBTL1 | |
| SCHEMBL28440902 | 0.88 | PSMD14 (0.61) | KMT2AMEN1MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL23052580 | 0.88 | PSMD14 (0.61) | KMT2AMEN1MAPTNPSR1L3MBTL1 | |
| SCHEMBL23052112 | 0.88 | KMT2A (0.71) | KMT2AMEN1MAPTNPSR1L3MBTL1 | |
| SCHEMBL30435021 | 0.86 | KMT2A (0.53) | KMT2AMEN1MAPTNPSR1L3MBTL1 | |
| SCHEMBL28442689 | 0.86 | KMT2A (0.53) | KMT2AMEN1MAPTNPSR1L3MBTL1 | |
| SCHEMBL28450609 | 0.86 | KMT2A (0.53) | KMT2AMEN1MAPTNPSR1L3MBTL1 | |
| SCHEMBL30435684 | 0.85 | MAPT (0.76) | KMT2AMEN1MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL28450973 | 0.83 | MAOA (0.67) | KMT2AMEN1MAPTL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111423374-B | Dihydropyrazole sulfonamide compound and preparation method and application thereof | 合肥工业大学 | 2023-03-21 | — | — | CN | disclosed |
| CN-111423374-A | Dihydropyrazole sulfonamide compound and preparation method and application thereof | 合肥工业大学 | 2020-07-17 | — | — | CN | disclosed |