Methacrylic Acid

Methacrylic Acid

SCHEMBL28898117

C=C(C)C(=O)NCc1ccccc1.C=C(C)C(=O)O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
MAPT P10636 1/20 0.56
CYP2C9 P11712 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
EPHX1 P07099 1/20 0.50
HPGD P15428 1/20 0.50
PLAAT3 P53816 1/20 0.49
PLAAT5 Q96KN8 1/20 0.49
PLAAT2 Q9NWW9 1/20 0.49
PLAAT4 Q9UL19 1/20 0.49
PTPN1 P18031 1/20 0.49
GAA P10253 1/20 0.49
EPHX2 P34913 1/20 0.47
RIPK1 Q13546 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL183463 0.96 ALDH1A1 (0.59) ALDH1A1MEN1KMT2AMAPTCYP2C9
SCHEMBL731190 0.87 KMT2A (0.50) ALDH1A1MEN1KMT2AMAPTL3MBTL1
Methacrylic Acid SCHEMBL3949680 0.84 CYP2C9 (0.53) ALDH1A1MEN1KMT2AMAPTCYP2C9
SCHEMBL730868 0.84 POLB (0.53) ALDH1A1MEN1KMT2AMAPTSMN1; SMN2
SCHEMBL204358 0.83 HDAC1 (0.51) ALDH1A1MEN1KMT2AMAPTL3MBTL1
SCHEMBL8903624 0.83 TP53 (0.58) ALDH1A1MEN1KMT2AMAPTCYP2C9
SCHEMBL204253 0.82 MAPK14 (0.58) ALDH1A1MEN1KMT2ASMN1; SMN2HPGD
SCHEMBL4971236 0.82 EPHX2 (0.57) ALDH1A1CYP2C9L3MBTL1EPHX1HPGD
N-Benzylmethylamine SCHEMBL27722064 0.81 MAPT (0.63) ALDH1A1MEN1KMT2AMAPTCYP2C9
SCHEMBL6658418 0.81 ALDH1A1 (0.54) ALDH1A1MEN1KMT2AMAPTCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111471127-B Amidated binary polymer diesel pour point depressant and preparation and application thereof 上海应用技术大学 2022-06-14 CN disclosed
CN-111471127-B Amidated binary polymer diesel pour point depressant and preparation and application thereof 上海应用技术大学 2022-06-14 CN disclosed
CN-111471127-A Amidated binary polymer diesel pour point depressant and preparation and application thereof 上海应用技术大学 2020-07-31 CN disclosed
CN-111471127-A Amidated binary polymer diesel pour point depressant and preparation and application thereof 上海应用技术大学 2020-07-31 CN disclosed