SCHEMBL730868

SCHEMBL730868

C=C(C)C(=O)NCc1cccc(CNC(=O)C(=C)C)c1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
ALDH1A1 P00352 5/20 0.49
HPGD P15428 1/20 0.49
TDP1 Q9NUW8 2/20 0.46
ESR1 P03372 1/20 0.46
MAPT P10636 3/20 0.46
LMNA P02545 2/20 0.46
PKM P14618 2/20 0.46
ALOX12 P18054 1/20 0.46
KDM4E B2RXH2 1/20 0.44
NOS2 P35228 1/20 0.43
FBP1 P09467 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CYP19A1 P11511 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5348027 0.90 GABRP (0.51) POLBMEN1KMT2AMAPTLMNA
SCHEMBL16594646 0.89 NAMPT (0.46) POLBMEN1KMT2AALDH1A1HPGD
SCHEMBL183463 0.87 ALDH1A1 (0.59) MEN1KMT2AALDH1A1HPGDMAPT
SCHEMBL8472235 0.86 ALDH1A1 (0.63) POLBMEN1KMT2AALDH1A1HPGD
SCHEMBL731190 0.84 KMT2A (0.50) POLBMEN1KMT2AALDH1A1MAPT
Methacrylic Acid SCHEMBL28898117 0.84 ALDH1A1 (0.56) MEN1KMT2AALDH1A1HPGDMAPT
SCHEMBL16594594 0.83 PTPN1 (0.56) POLBMEN1KMT2AALDH1A1HPGD
SCHEMBL339753 0.81 ERCC1 (0.59) ALDH1A1HPGDMAPTLMNAKDM4E
SCHEMBL1899410 0.80 NPSR1 (0.57) POLBMEN1KMT2AALDH1A1HPGD
SCHEMBL28370739 0.80 TGM2 (0.53) POLBMEN1KMT2AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3063210-A2 METHOD OF THIOPHENOL REMOVAL FROM POLY(ARYLENE SULFIDE) POLYMER COMPOSITIONS SOLVAY SA (BE) 2016-09-07 EP disclosed
US-9388282-B2 Method of thiophenol removal from poly(arylene sulfide) polymer compositions SOLVAY SPECIALTY POLYMERS USA, LLC. (US) 2016-07-12 US disclosed
WO-2015065906-A2 METHOD OF THIOPHENOL REMOVAL FROM POLY(ARYLENE SULFIDE) POLYMER COMPOSITIONS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2015-05-07 WO disclosed
US-20150119550-A1 Method of Thiophenol Removal from Poly(Arylene Sulfide) Polymer Compositions CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2015-04-30 US disclosed
US-8889802-B2 Polymer compositions and methods of making and using same POLYMERIGHT, INC. (US) 2014-11-18 US disclosed
US-20120130040-A1 Polymer Compositions and Methods of Making and Using Same POLYMERIGHT, INC. (US) 2012-05-24 US disclosed
EP-2448990-A1 POLYMER COMPOSITIONS AND METHODS OF MAKING AND USING SAME Polymeright Inc. (US) 2012-05-09 EP disclosed
US-8138278-B2 Polymer compositions and methods of making and using same POLYMERIGHT, INC. (US) 2012-03-20 US disclosed
US-20110152492-A1 Polymer Compositions and Methods of Making and Using Same POLYMERIGHT, INC. (US) 2011-06-23 US disclosed
WO-2011008480-A1 POLYMER COMPOSITIONS AND METHODS OF MAKING AND USING SAME POLYMERIGHT, INC. (US) 2011-01-20 WO disclosed
US-7585932-B2 Polymer compositions and processes for making and using same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2009-09-08 US disclosed
EP-1940917-A2 POLYMER COMPOSITIONS AND PROCESSES FOR MAKING AND USING SAME Chevron Phillips Chemical Company LP (US) 2008-07-09 EP disclosed
US-20070055033-A1 POLYMER COMPOSITIONS AND PROCESSES FOR MAKING AND USING SAME CHEVRON PHILLIPS CHEMICAL COMPANY, LP 2007-03-08 US disclosed
WO-2007021960-A2 POLYMER COMPOSITIONS AND PROCESSES FOR MAKING AND USING SAME CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2007-02-22 WO disclosed