Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28484401 | 0.88 | — | — | |
| SCHEMBL28898150 | 0.80 | TSHR (0.42) | USP2KMT2ANPC1MAPTRAB9A | |
| SCHEMBL25645225 | 0.79 | USP2 (0.42) | USP2KMT2ANPC1MAPTRAB9A | |
| SCHEMBL28898147 | 0.78 | TSHR (0.43) | USP2NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL28898160 | 0.77 | TSHR (0.42) | USP2MAPTSMN1; SMN2 | |
| SCHEMBL28898144 | 0.76 | KMT2A (0.41) | USP2KMT2ANPC1MAPTRAB9A | |
| SCHEMBL28491214 | 0.76 | USP2 (0.38) | USP2KMT2A | |
| SCHEMBL21427958 | 0.76 | USP2 (0.38) | USP2KMT2A | |
| SCHEMBL28898135 | 0.76 | TSHR (0.41) | USP2MAPTSMN1; SMN2 | |
| SCHEMBL28898154 | 0.76 | SLC10A1 (0.46) | NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111868026-B | Capsid protein assembly inhibitor containing N-heterocyclic five-membered ring, pharmaceutical composition and application thereof | 正大天晴药业集团股份有限公司 | 2022-11-25 | — | — | CN | disclosed |