Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9637625 | 0.88 | NPC1 (0.56) | KMT2ALMNAMEN1GAATHRB | |
| SCHEMBL10745616 | 0.85 | KMT2A (0.53) | KMT2ALMNAMEN1GAATHRB | |
| SCHEMBL9638868 | 0.81 | BRD4 (0.48) | KMT2ALMNAMEN1GAATHRB | |
| SCHEMBL25838729 | 0.80 | NPC1 (0.49) | KMT2ALMNAMEN1GAATHRB | |
| SCHEMBL4930503 | 0.79 | SHMT2 (0.48) | KMT2ALMNAMEN1GAATHRB | |
| SCHEMBL4916892 | 0.78 | KMT2A (0.49) | KMT2ALMNAMEN1GAANPC1 | |
| SCHEMBL22589894 | 0.78 | METAP1 (0.51) | KMT2ALMNAMEN1GAATHRB | |
| SCHEMBL3237870 | 0.78 | NPC1 (0.54) | KMT2ALMNAMEN1GAATHRB | |
| SCHEMBL31419067 | 0.77 | ALDH1A1 (0.46) | KMT2ALMNAMEN1GAATHRB | |
| SCHEMBL1620480 | 0.77 | KMT2A (0.43) | KMT2ALMNAMEN1GAATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115380032-A | KV3 enhancers for the treatment of cognitive disorders | 豪夫迈·罗氏有限公司 | 2022-11-22 | — | — | CN | disclosed |