Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 9/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 9/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 11/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 11/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29180308 | 0.80 | — | — | |
| SCHEMBL4538917 | 0.76 | HTR3E (0.39) | POLB | |
| SCHEMBL30827713 | 0.68 | POLB (0.43) | CHRNB4CHRNA3POLBCHRNB2CHRNA4 | |
| SCHEMBL29998481 | 0.67 | CHRNB4 (0.61) | CHRNB4CHRNA3POLBCHRNB2CHRNA4 | |
| SCHEMBL27552787 | 0.65 | POLB (0.40) | CHRNB4CHRNA3POLBCHRNB2CHRNA4 | |
| SCHEMBL27594106 | 0.64 | CHRNB4 (0.58) | CHRNB4CHRNA3POLBCHRNB2CHRNA4 | |
| SCHEMBL27057850 | 0.64 | CHRNB4 (0.58) | CHRNB4CHRNA3POLBCHRNB2CHRNA4 | |
| SCHEMBL2923088 | 0.64 | CHRNB2 (0.64) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL3069993 | 0.63 | CHRNB2 (0.62) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL22199019 | 0.63 | CYP2E1 (0.56) | CHRNB4CHRNA3POLBCHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115380032-A | KV3 enhancers for the treatment of cognitive disorders | 豪夫迈·罗氏有限公司 | 2022-11-22 | — | — | CN | disclosed |