Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30025407 | 1.00 | HSD11B1 (0.37) | HSD11B1ALPIPDGFRBFGFR1FGFR3 | |
| SCHEMBL28898552 | 1.00 | HSD11B1 (0.37) | HSD11B1ALPIPDGFRBFGFR1FGFR3 | |
| SCHEMBL28898553 | 0.83 | MAPT (0.38) | METAP2KMT2AMEN1NPC1HSP90AA1 | |
| SCHEMBL28898577 | 0.83 | NR1H2 (0.40) | ALPIKMT2AMEN1CA12CA9 | |
| SCHEMBL28898556 | 0.83 | MAPT (0.38) | METAP2KMT2AMEN1NPC1HSP90AA1 | |
| SCHEMBL30025843 | 0.83 | MAPT (0.38) | METAP2KMT2AMEN1NPC1HSP90AA1 | |
| SCHEMBL30024906 | 0.83 | NR1H2 (0.40) | ALPIKMT2AMEN1CA12CA9 | |
| SCHEMBL28898584 | 0.83 | NR1H2 (0.40) | ALPIKMT2AMEN1CA12CA9 | |
| SCHEMBL28960027 | 0.80 | STK17B (0.37) | KMT2AMEN1NPC1RAB9A | |
| SCHEMBL30026278 | 0.80 | STK17B (0.37) | KMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109336845-B | Optically active cyclopentane-3-imine and its derivative and preparation method | 西华师范大学 | 2022-11-01 | — | — | CN | claimed |
| CN-109336845-B | Optically active cyclopentane-3-imine and its derivative and preparation method | 西华师范大学 | 2022-11-01 | — | — | CN | disclosed |